Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CRG85_RS01810 Genome accession   NZ_CP034787
Coordinates   397977..398609 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ECCNB20-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 392977..403609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRG85_RS01785 (CRG85_01785) yhfG 393109..393276 (+) 168 WP_000736860.1 YhfG family protein -
  CRG85_RS01790 (CRG85_01790) fic 393266..393868 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CRG85_RS01795 (CRG85_01795) pabA 393900..394463 (+) 564 WP_085452727.1 aminodeoxychorismate synthase component 2 -
  CRG85_RS01800 (CRG85_01800) argD 394549..395769 (+) 1221 WP_077492861.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CRG85_RS01805 (CRG85_01805) yhfK 395836..397926 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CRG85_RS01810 (CRG85_01810) crp 397977..398609 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CRG85_RS01815 (CRG85_01815) yhfA 398911..399315 (+) 405 WP_001148910.1 OsmC family protein -
  CRG85_RS01820 (CRG85_01820) prkB 399370..400239 (-) 870 WP_001274680.1 phosphoribulokinase -
  CRG85_RS01825 (CRG85_01825) yheU 400293..400511 (-) 219 WP_000907085.1 YheU family protein -
  CRG85_RS01830 (CRG85_01830) yheT 400505..401527 (-) 1023 WP_001753125.1 hydrolase -
  CRG85_RS01835 (CRG85_01835) yheS 401527..403440 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290732 CRG85_RS01810 WP_000242755.1 397977..398609(-) (crp) [Escherichia coli strain ECCNB20-2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290732 CRG85_RS01810 WP_000242755.1 397977..398609(-) (crp) [Escherichia coli strain ECCNB20-2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467