Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EM854_RS15265 Genome accession   NZ_CP034738
Coordinates   3100484..3101074 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain L65     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3095484..3106074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EM854_RS15250 (EM854_15250) uhpT 3096124..3097515 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EM854_RS15255 (EM854_15255) uhpC 3097653..3098972 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EM854_RS15260 (EM854_15260) uhpB 3098982..3100484 (-) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EM854_RS15265 (EM854_15265) letA 3100484..3101074 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EM854_RS15270 (EM854_15270) ilvN 3101149..3101439 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EM854_RS15275 (EM854_15275) ilvB 3101443..3103131 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EM854_RS15280 (EM854_15280) ivbL 3103237..3103335 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EM854_RS15285 (EM854_15285) tisB 3103900..3103989 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EM854_RS24825 ysdE 3104252..3104326 (-) 75 WP_211180519.1 protein YsdE -
  EM854_RS15290 (EM854_15290) emrD 3104408..3105592 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=290618 EM854_RS15265 WP_000633668.1 3100484..3101074(-) (letA) [Escherichia coli strain L65]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=290618 EM854_RS15265 WP_000633668.1 3100484..3101074(-) (letA) [Escherichia coli strain L65]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment