Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DK245_RS01210 Genome accession   NZ_CP034595
Coordinates   253988..254620 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain WCHEC035053S1G0     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 248988..259620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK245_RS01185 (DK245_001185) yhfG 249120..249287 (+) 168 WP_000736862.1 YhfG family protein -
  DK245_RS01190 (DK245_001190) fic 249277..249879 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  DK245_RS01195 (DK245_001195) pabA 249911..250474 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  DK245_RS01200 (DK245_001200) argD 250560..251780 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DK245_RS01205 (DK245_001205) yhfK 251847..253937 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  DK245_RS01210 (DK245_001210) crp 253988..254620 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DK245_RS01215 (DK245_001215) yhfA 254922..255326 (+) 405 WP_001148908.1 OsmC family protein -
  DK245_RS01220 (DK245_001220) prkB 255381..256250 (-) 870 WP_001274680.1 phosphoribulokinase -
  DK245_RS01225 (DK245_001225) yheU 256304..256522 (-) 219 WP_000907085.1 YheU family protein -
  DK245_RS01230 (DK245_001230) yheT 256516..257538 (-) 1023 WP_000057356.1 hydrolase -
  DK245_RS01235 (DK245_001235) yheS 257538..259451 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290304 DK245_RS01210 WP_000242755.1 253988..254620(-) (crp) [Escherichia coli strain WCHEC035053S1G0]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290304 DK245_RS01210 WP_000242755.1 253988..254620(-) (crp) [Escherichia coli strain WCHEC035053S1G0]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment