Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EKM58_RS20890 Genome accession   NZ_CP034589
Coordinates   4263102..4263734 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain L37     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4258102..4268734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM58_RS20865 (EKM58_20865) yheS 4258271..4260184 (+) 1914 WP_126675499.1 ABC transporter ATP-binding protein -
  EKM58_RS20870 (EKM58_20870) yheT 4260184..4261206 (+) 1023 WP_000057356.1 hydrolase -
  EKM58_RS20875 (EKM58_20875) yheU 4261200..4261418 (+) 219 WP_000907085.1 YheU family protein -
  EKM58_RS20880 (EKM58_20880) prkB 4261472..4262341 (+) 870 WP_001274680.1 phosphoribulokinase -
  EKM58_RS20885 (EKM58_20885) yhfA 4262396..4262800 (-) 405 WP_001148908.1 OsmC family protein -
  EKM58_RS20890 (EKM58_20890) crp 4263102..4263734 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EKM58_RS20895 (EKM58_20895) yhfK 4263785..4265875 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EKM58_RS20900 (EKM58_20900) argD 4265942..4267162 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EKM58_RS20905 (EKM58_20905) pabA 4267248..4267811 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EKM58_RS20910 (EKM58_20910) fic 4267843..4268445 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EKM58_RS20915 (EKM58_20915) yhfG 4268435..4268602 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290291 EKM58_RS20890 WP_000242755.1 4263102..4263734(+) (crp) [Escherichia coli strain L37]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290291 EKM58_RS20890 WP_000242755.1 4263102..4263734(+) (crp) [Escherichia coli strain L37]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment