Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EJF26_RS09070 Genome accession   NZ_CP034442
Coordinates   1778093..1778725 (+) Length   210 a.a.
NCBI ID   WP_000698446.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1773093..1783725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS09045 mvaD 1773291..1774244 (+) 954 WP_000373464.1 diphosphomevalonate decarboxylase -
  EJF26_RS09050 - 1774231..1775238 (+) 1008 WP_000562386.1 phosphomevalonate kinase -
  EJF26_RS09055 fni 1775222..1776223 (+) 1002 WP_000210643.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EJF26_RS09060 liaF 1776389..1777087 (+) 699 WP_000714486.1 cell wall-active antibiotics response protein LiaF -
  EJF26_RS09065 - 1777084..1778082 (+) 999 WP_000744934.1 sensor histidine kinase -
  EJF26_RS09070 vraR 1778093..1778725 (+) 633 WP_000698446.1 response regulator transcription factor Regulator
  EJF26_RS09075 - 1778726..1779382 (+) 657 WP_000050042.1 DNA alkylation repair protein -
  EJF26_RS09080 tig 1779475..1780758 (+) 1284 WP_000116512.1 trigger factor -
  EJF26_RS09085 recD/recD2/recDB 1780806..1783172 (-) 2367 WP_000454466.1 ATP-dependent RecD-like DNA helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23588.21 Da        Isoelectric Point: 4.8942

>NTDB_id=289824 EJF26_RS09070 WP_000698446.1 1778093..1778725(+) (vraR) [Streptococcus oralis subsp. dentisani strain F0392]
MKILLVDDHEMVRLGLKSYFDLQDDVKVVGEAANGAQGIDLALELRPDVIVMDIVMPEMNGIDATLALLKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=289824 EJF26_RS09070 WP_000698446.1 1778093..1778725(+) (vraR) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTTCGATTGGGCTTGAAAAGCTATTTTGACCTCCAAGACGATGTGAA
AGTTGTAGGCGAGGCTGCCAATGGGGCTCAAGGTATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTGGCCCTCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTC
ACATCTTACTTGGATAATGAAAAAATCATGCCGGTCTTGAATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGACGAACTGCTTCATGCAGTTCGTAAGGTGGCAGCGGGCGAGCTTGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGCAATCATATGGAACTTCATGAGGAATTGACTGCGCGTGAACGAGATGTGCTTCAACTCATCGCCAAGGGCTAC
GAAAATCAACGGATCGCAGATGAACTCTTCATTTCTCTCAAGACGGTTAAGACCCACGTGTCCAATATCCTTGCCAAACT
TGAAGTCAGTGATCGCACCCAGGCTGCGGTCTATGCCTTTCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.675

99.524

0.514
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41