Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EJC75_RS17955 Genome accession   NZ_CP034404
Coordinates   3292991..3293581 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CRE10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3287991..3298581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJC75_RS17940 (EJC75_17940) uhpT 3288631..3290022 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EJC75_RS17945 (EJC75_17945) uhpC 3290160..3291479 (-) 1320 WP_024198525.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EJC75_RS17950 (EJC75_17950) uhpB 3291489..3292991 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EJC75_RS17955 (EJC75_17955) letA 3292991..3293581 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EJC75_RS17960 (EJC75_17960) ilvN 3293656..3293946 (-) 291 WP_001181713.1 acetolactate synthase small subunit -
  EJC75_RS17965 (EJC75_17965) ilvB 3293950..3295638 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EJC75_RS17970 (EJC75_17970) ivbL 3295744..3295842 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EJC75_RS17975 (EJC75_17975) tisB 3296406..3296495 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EJC75_RS26570 ysdE 3296758..3296832 (-) 75 WP_211180519.1 protein YsdE -
  EJC75_RS17980 (EJC75_17980) emrD 3296914..3298100 (+) 1187 Protein_3131 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=289499 EJC75_RS17955 WP_000633668.1 3292991..3293581(-) (letA) [Escherichia coli strain CRE10]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=289499 EJC75_RS17955 WP_000633668.1 3292991..3293581(-) (letA) [Escherichia coli strain CRE10]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment