Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EJH97_RS02060 Genome accession   NZ_CP034389
Coordinates   455573..456205 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RS571     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 450573..461205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJH97_RS02035 (EJH97_02035) yhfG 450706..450873 (+) 168 WP_022646195.1 YhfG family protein -
  EJH97_RS02040 (EJH97_02040) fic 450863..451465 (+) 603 WP_022646194.1 putative adenosine monophosphate-protein transferase Fic -
  EJH97_RS02045 (EJH97_02045) pabA 451497..452060 (+) 564 WP_022646193.1 aminodeoxychorismate synthase component 2 -
  EJH97_RS02050 (EJH97_02050) argD 452146..453369 (+) 1224 WP_029391651.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EJH97_RS02055 (EJH97_02055) yhfK 453432..455522 (-) 2091 WP_128896981.1 YccS/YhfK family putative transporter -
  EJH97_RS02060 (EJH97_02060) crp 455573..456205 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EJH97_RS02065 (EJH97_02065) yhfA 456507..456911 (+) 405 WP_001148908.1 OsmC family protein -
  EJH97_RS02070 (EJH97_02070) prkB 456966..457835 (-) 870 WP_001274680.1 phosphoribulokinase -
  EJH97_RS02075 (EJH97_02075) yheU 457889..458107 (-) 219 WP_000907085.1 YheU family protein -
  EJH97_RS02080 (EJH97_02080) yheT 458101..459123 (-) 1023 WP_022646191.1 hydrolase -
  EJH97_RS02085 (EJH97_02085) yheS 459123..461036 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=289327 EJH97_RS02060 WP_000242755.1 455573..456205(-) (crp) [Escherichia coli strain RS571]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=289327 EJH97_RS02060 WP_000242755.1 455573..456205(-) (crp) [Escherichia coli strain RS571]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467