Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EJB16_RS23725 Genome accession   NZ_CP034384
Coordinates   4731793..4732383 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O157:H7 strain FRIK804     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4726793..4737383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJB16_RS23710 (EJB16_24500) uhpT 4727433..4728824 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EJB16_RS23715 (EJB16_24505) uhpC 4728962..4730281 (-) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EJB16_RS23720 (EJB16_24510) uhpB 4730291..4731793 (-) 1503 WP_115455539.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EJB16_RS23725 (EJB16_24515) letA 4731793..4732383 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EJB16_RS23730 (EJB16_24520) - 4732545..4733648 (-) 1104 WP_001089794.1 hypothetical protein -
  EJB16_RS23735 (EJB16_24525) - 4734256..4734738 (-) 483 WP_000229982.1 hypothetical protein -
  EJB16_RS23740 (EJB16_24530) - 4734886..4735539 (-) 654 WP_000168040.1 hypothetical protein -
  EJB16_RS23745 (EJB16_24535) ilvN 4735802..4736092 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=289299 EJB16_RS23725 WP_000633668.1 4731793..4732383(-) (letA) [Escherichia coli O157:H7 strain FRIK804]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=289299 EJB16_RS23725 WP_000633668.1 4731793..4732383(-) (letA) [Escherichia coli O157:H7 strain FRIK804]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGTGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCACTAACCAAACGTGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378