Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EGA47_RS03635 Genome accession   NZ_CP034106
Coordinates   808632..809264 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RCAD0514     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 803632..814264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGA47_RS03610 (EGA47_03665) yhfG 803764..803931 (+) 168 WP_000736862.1 YhfG family protein -
  EGA47_RS03615 (EGA47_03670) fic 803921..804523 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EGA47_RS03620 (EGA47_03675) pabA 804555..805118 (+) 564 WP_072731852.1 aminodeoxychorismate synthase component 2 -
  EGA47_RS03625 (EGA47_03680) argD 805204..806424 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EGA47_RS03630 (EGA47_03685) yhfK 806491..808581 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EGA47_RS03635 (EGA47_03690) crp 808632..809264 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EGA47_RS03640 (EGA47_03695) yhfA 809566..809970 (+) 405 WP_001148908.1 OsmC family protein -
  EGA47_RS03645 (EGA47_03700) prkB 810025..810894 (-) 870 WP_001274680.1 phosphoribulokinase -
  EGA47_RS03650 (EGA47_03705) yheU 810948..811166 (-) 219 WP_000907085.1 YheU family protein -
  EGA47_RS03655 (EGA47_03710) yheT 811160..812182 (-) 1023 WP_000057356.1 hydrolase -
  EGA47_RS03660 (EGA47_03715) yheS 812182..814095 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=287898 EGA47_RS03635 WP_000242755.1 808632..809264(-) (crp) [Escherichia coli strain RCAD0514]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=287898 EGA47_RS03635 WP_000242755.1 808632..809264(-) (crp) [Escherichia coli strain RCAD0514]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment