Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EHU52_RS01925 Genome accession   NZ_CP034071
Coordinates   375021..376997 (+) Length   658 a.a.
NCBI ID   WP_124732947.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpbs1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 370021..381997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHU52_RS01905 ggt 371107..372810 (+) 1704 WP_124732945.1 gamma-glutamyltransferase -
  EHU52_RS01910 - 373095..373865 (+) 771 WP_124732946.1 HP1117 family Sel1-like repeat protein -
  EHU52_RS07985 - 374068..374268 (-) 201 Protein_363 hypothetical protein -
  EHU52_RS01920 - 374380..374981 (+) 602 Protein_364 DUF1542 domain-containing protein -
  EHU52_RS01925 uvrB 375021..376997 (+) 1977 WP_124732947.1 excinuclease ABC subunit UvrB Machinery gene
  EHU52_RS01930 - 376994..377827 (-) 834 WP_124732948.1 outer membrane protein -
  EHU52_RS01935 purB 377890..379212 (-) 1323 WP_124732949.1 adenylosuccinate lyase -
  EHU52_RS01940 - 379322..380266 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  EHU52_RS01945 - 380279..381502 (-) 1224 WP_001097079.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  EHU52_RS01950 - 381513..381905 (-) 393 WP_000656175.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75963.58 Da        Isoelectric Point: 7.0841

>NTDB_id=287593 EHU52_RS01925 WP_124732947.1 375021..376997(+) (uvrB) [Helicobacter pylori strain Hpbs1]
MPLFDLKSPYPPAGDQPKAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISTTGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=287593 EHU52_RS01925 WP_124732947.1 375021..376997(+) (uvrB) [Helicobacter pylori strain Hpbs1]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCAAAAGCCATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAAACTTATACGATGGCTAATATCATCGCTC
AAATCAATAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCACATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCAGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCTTATAAGAGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAACGCTTGGATTCTGTC
ATGCTTTATGCAGCCAGTCAGTTTGCCGTAGGGAGTGAGAGACTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCACAACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
TTAGAATTAGAGCTTTCTAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAACGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGATGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATACCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497