Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EGH14_RS06200 Genome accession   NZ_CP034024
Coordinates   1045858..1047885 (-) Length   675 a.a.
NCBI ID   WP_003688978.1    Uniprot ID   Q50939
Organism   Neisseria gonorrhoeae strain FQ35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1040858..1052885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH14_RS06175 (EGH14_06175) - 1041600..1042984 (+) 1385 Protein_1067 tetratricopeptide repeat protein -
  EGH14_RS06180 (EGH14_06180) trmB 1043126..1043842 (+) 717 WP_003688973.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  EGH14_RS06190 (EGH14_06190) - 1044166..1044513 (+) 348 WP_010357745.1 hypothetical protein -
  EGH14_RS06195 (EGH14_06195) cah 1044922..1045680 (+) 759 WP_003688976.1 carbonic anhydrase -
  EGH14_RS06200 (EGH14_06200) uvrB 1045858..1047885 (-) 2028 WP_003688978.1 excinuclease ABC subunit UvrB Machinery gene
  EGH14_RS06205 (EGH14_06205) - 1048215..1049690 (-) 1476 WP_003691337.1 S41 family peptidase -
  EGH14_RS06210 (EGH14_06210) - 1049817..1051613 (-) 1797 WP_124723919.1 peptidoglycan DD-metalloendopeptidase family protein -
  EGH14_RS06220 (EGH14_06220) - 1051940..1052500 (+) 561 WP_003692938.1 CreA family protein -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 76989.44 Da        Isoelectric Point: 5.0489

>NTDB_id=287261 EGH14_RS06200 WP_003688978.1 1045858..1047885(-) (uvrB) [Neisseria gonorrhoeae strain FQ35]
MEVIRYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
HQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAVDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKL
EKAMQQAARDLQFEEAAVLRDRIRNIKENLLFGAE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=287261 EGH14_RS06200 WP_003688978.1 1045858..1047885(-) (uvrB) [Neisseria gonorrhoeae strain FQ35]
ATGGAAGTCATCCGATACCCAAATTCCCCCTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCCACCGCCAT
TGCGGGCCTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CGATGGCGAACGTCATCGCGCAAAGCGGCAGACCCGCCATCATTATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCCGAAAACGCAGTGGAATATTTCGTGTCGTATTACGACTATTACCAGCCCGAAGCCTA
TGTGCCCAGCCGCGATTTGTTCATCGAAAAAGACAGCGCGATCAACGAACACATCGAGCAGATGCGCCTTTCCGCCACCA
AAAACCTGATGACGCGCGACGACGTGATTATCGTCGCCACCGTGTCCGCCATTTACGGTATCGGCGACCCGACCGAGTAT
CAACAAATGGTGCTGTCCGTAAAAGAAGGCGACACCATCGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAACGCGGCGATTTGGACTTCAAACGCGGCAGCTTCCGCGTGCGCGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGTATCAGCCTGTTTGATGACGAAATCGACCGCCTCGATATGTTCGACCCGCTTTCAGGCAGCCTG
CACCAGCGTGTCGGACGCTACACCGTCTTCCCGTCCAGCCACTACGTTACCCCGCGCGACACCGTATTGCGCGCCTGCGA
ATCCATCAAAGAAGAATTGCGCGAACGCATCGAATTTTTCGCTCGCGAACAACGCCCCGTCGAGCAACAACGCATCGAAC
AGCGCACCCGTTTCGACCTCGAAATGCTCTACGAAATGGGCTTCTGCAAAGGCATTGAAAACTACTCCCGCCACTTCTCC
GGTAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCCGACAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTTACCCAAATCGGCGGCATGTACAAAGGCGACGCATCGCGCAAGCAAAACCTCGTGGACTACGGCTTCCGCC
TGCCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCACGAATTTGAAAAAGTCATGCCGCAAACCGTCTTCGTTTCCGCC
ACCCCCGCGAAATACGAAGAAGAACACGCCGGACAAGTCGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCCCA
AATCATCATCCGCCCCGTCGCCACCCAAGTCGACGATTTAATGAGCGAAATCAACGACCGTATTCAAAAAGGCGAACGTG
TGCTCGTTACCACCCTCACCAAACGCATGGCGGAGCAACTTACCGACTATTACAGCGAACTCGGCATCAAAGTGCGCTAC
CTGCACAGCGACATCGACACCGTCGAGCGCGTTGAAATCATTAGAGATTTGCGGCTCGGCCTGTTTGACGTACTCGTTGG
CATCAACCTGTTGCGCGAAGGCCTCGACATCCCCGAAGTGTCCCTCGTCGCCATCCTCGATGCCGACAAAGAAGGCTTCC
TGCGCTCCCACCGCAGCCTGATTCAAACCATAGGCCGCGCCGCGCGCAACGTGAACGGCGTCGCCATCCTGTACGCCGAC
AAAATTACCGACTCCATGAAAGCCGCCGTCGACGAAACCGAACGCCGCCGCGAAAAACAGATTAAATTCAACGAAGAACA
CGGTATCGTGCCGCAGCAGATTAAAAAACAGGTCAAAGACATCATCGACGGCGTGTACCACGAAGAAGACAGTGGCAAAG
GCCGTAGACAAGGCAAAAACAAGGTCAAAGTCGGCGAAATCCACAACGAAGAAGACGCGATTAAAGAAATCGCCAAACTG
GAAAAAGCCATGCAGCAGGCGGCTAGGGATTTACAGTTTGAAGAAGCTGCTGTGTTGAGGGATAGGATTAGGAATATTAA
AGAGAATTTGTTGTTTGGGGCGGAGTGA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

Type III restriction enzyme, res subunit (ResIII)

(23-144)

UvrB interaction domain (UvrB_inter)

(165-255)

UvrB/uvrC motif (UVR)

(635-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q50939

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.204

98.222

0.542
  uvrB Streptococcus pneumoniae R6

55.204

98.222

0.542
  uvrB Streptococcus pneumoniae D39

55.204

98.222

0.542

Multiple sequence alignment