Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV/pilI   Type   Regulator
Locus tag   EGH12_RS07730 Genome accession   NZ_CP034020
Coordinates   1318881..1319495 (-) Length   204 a.a.
NCBI ID   WP_012503479.1    Uniprot ID   B4RKG4
Organism   Neisseria gonorrhoeae strain FQ48     
Function   repress natural transformation; antagonize ComP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1313881..1324495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH12_RS07695 (EGH12_07695) dapC 1313897..1315084 (-) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -
  EGH12_RS07700 (EGH12_07700) dut 1315156..1315608 (-) 453 WP_003701071.1 dUTP diphosphatase -
  EGH12_RS07705 (EGH12_07705) - 1315774..1316485 (+) 712 Protein_1329 AzlC family ABC transporter permease -
  EGH12_RS07710 (EGH12_07710) - 1316482..1316790 (+) 309 WP_003706588.1 AzlD family protein -
  EGH12_RS07715 (EGH12_07715) pilL 1316860..1317333 (-) 474 WP_012503482.1 PilX family type IV pilin Machinery gene
  EGH12_RS07720 (EGH12_07720) pilK 1317335..1317943 (-) 609 WP_047921847.1 pilus assembly protein Machinery gene
  EGH12_RS07725 (EGH12_07725) pilJ 1317922..1318884 (-) 963 WP_047921846.1 PilW family protein Machinery gene
  EGH12_RS07730 (EGH12_07730) pilV/pilI 1318881..1319495 (-) 615 WP_012503479.1 type IV pilus modification protein PilV Regulator
  EGH12_RS07735 (EGH12_07735) pilH 1319527..1320189 (-) 663 WP_047916986.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  EGH12_RS07740 (EGH12_07740) dnaB 1320446..1321849 (-) 1404 WP_012503477.1 replicative DNA helicase -
  EGH12_RS07750 (EGH12_07750) - 1322013..1322594 (+) 582 WP_003690895.1 superoxide dismutase -
  EGH12_RS07760 (EGH12_07760) - 1322826..1323335 (-) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  EGH12_RS07765 (EGH12_07765) - 1323665..1323997 (-) 333 WP_003687908.1 hypothetical protein -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 22099.99 Da        Isoelectric Point: 4.9673

>NTDB_id=287119 EGH12_RS07730 WP_012503479.1 1318881..1319495(-) (pilV/pilI) [Neisseria gonorrhoeae strain FQ48]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTGPYTPTPSGGDFKLNNNNLISKKDLAKAQLDRFDYELRNALPDAVAIHYAVCKDSSGGAPTLSGGTFSPNCDNKA
NGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGHE

Nucleotide


Download         Length: 615 bp        

>NTDB_id=287119 EGH12_RS07730 WP_012503479.1 1318881..1319495(-) (pilV/pilI) [Neisseria gonorrhoeae strain FQ48]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACGGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGGGCCGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGCTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGATTATGAATTGAGAAACGCCTTGCCGGATGCGGTAGCTATTCATT
ACGCCGTCTGCAAGGATTCGTCGGGTGGCGCGCCGACATTGTCCGGCGGTACTTTTTCTCCAAATTGCGATAATAAGGCA
AACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAGGT
GAGCGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCATGAATGA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RKG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV/pilI Neisseria gonorrhoeae MS11

90.686

100

0.907
  pilV Neisseria meningitidis 8013

84.135

100

0.858