Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EGH12_RS07110 Genome accession   NZ_CP034020
Coordinates   1207444..1209471 (-) Length   675 a.a.
NCBI ID   WP_003691336.1    Uniprot ID   B4RMI9
Organism   Neisseria gonorrhoeae strain FQ48     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1202444..1214471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH12_RS07085 (EGH12_07085) - 1203186..1204590 (+) 1405 Protein_1215 tetratricopeptide repeat protein -
  EGH12_RS07090 (EGH12_07090) trmB 1204712..1205428 (+) 717 WP_003691335.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  EGH12_RS07100 (EGH12_07100) - 1205752..1206099 (+) 348 WP_010357745.1 hypothetical protein -
  EGH12_RS07105 (EGH12_07105) cah 1206508..1207266 (+) 759 WP_003688976.1 carbonic anhydrase -
  EGH12_RS07110 (EGH12_07110) uvrB 1207444..1209471 (-) 2028 WP_003691336.1 excinuclease ABC subunit UvrB Machinery gene
  EGH12_RS07115 (EGH12_07115) - 1209801..1211276 (-) 1476 WP_003691337.1 S41 family peptidase -
  EGH12_RS07120 (EGH12_07120) - 1211403..1213199 (-) 1797 WP_003691339.1 peptidoglycan DD-metalloendopeptidase family protein -
  EGH12_RS07130 (EGH12_07130) - 1213526..1214086 (+) 561 WP_003691340.1 CreA family protein -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 77015.52 Da        Isoelectric Point: 5.0489

>NTDB_id=287115 EGH12_RS07110 WP_003691336.1 1207444..1209471(-) (uvrB) [Neisseria gonorrhoeae strain FQ48]
MEVIRYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
HQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDALRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAVDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKL
EKAMQQAARDLQFEEAAVLRDRIRNIKENLLFGAE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=287115 EGH12_RS07110 WP_003691336.1 1207444..1209471(-) (uvrB) [Neisseria gonorrhoeae strain FQ48]
ATGGAAGTCATCCGATACCCAAATTCCCCCTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCCACCGCCAT
TGCGGGCCTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CGATGGCGAACGTCATCGCGCAAAGCGGCAGACCCGCCATCATTATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCCGAAAACGCAGTGGAATATTTCGTGTCGTATTACGACTATTACCAGCCCGAAGCCTA
TGTGCCCAGCCGCGATTTGTTCATCGAAAAAGACAGCGCGATCAACGAACACATCGAGCAGATGCGCCTTTCCGCCACCA
AAAACCTGATGACGCGCGACGACGTGATTATCGTCGCCACCGTGTCCGCCATTTACGGTATCGGCGACCCGACCGAGTAT
CAACAAATGGTGCTGTCCGTAAAAGAAGGCGACACCATCGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAACGCGGCGATTTGGACTTCAAACGCGGCAGCTTCCGCGTGCGCGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGTATCAGCCTGTTTGATGACGAAATCGACCGCCTCGATATGTTCGACCCGCTTTCAGGCAGCCTG
CACCAGCGTGTCGGACGCTACACCGTCTTCCCGTCCAGCCACTACGTTACCCCGCGCGACACCGTATTGCGCGCCTGCGA
ATCCATCAAAGAAGAATTGCGCGAACGCATCGAATTTTTCGCTCGCGAACAACGCCCCGTCGAGCAACAACGCATCGAAC
AGCGCACCCGTTTCGACCTCGAAATGCTCTACGAAATGGGCTTCTGCAAAGGCATTGAAAACTACTCCCGCCACTTCTCC
GGTAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCCGACAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTTACCCAAATCGGCGGCATGTACAAAGGCGACGCATTGCGCAAGCAAAACCTCGTGGACTACGGCTTCCGCC
TGCCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCACGAATTTGAAAAAGTCATGCCGCAAACCGTCTTCGTTTCCGCC
ACCCCCGCGAAATACGAAGAAGAACACGCCGGACAAGTCGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCCCA
AATCATCATCCGCCCCGTCGCCACCCAAGTCGACGATTTAATGAGCGAAATCAACGACCGTATTCAAAAAGGCGAACGTG
TGCTCGTTACCACCCTTACCAAACGCATGGCGGAGCAACTCACCGACTATTACAGCGAACTCGGCATCAAAGTGCGCTAC
CTGCACAGCGACATCGACACCGTCGAACGCGTTGAAATCATTAGAGATTTGCGGCTCGGCCTGTTTGACGTACTCGTTGG
CATCAACCTGTTGCGCGAAGGCCTCGACATCCCCGAAGTCTCCCTCGTCGCCATCCTCGATGCCGACAAAGAAGGCTTCC
TGCGCTCCCACCGCAGCCTGATTCAAACCATAGGCCGCGCCGCGCGCAACGTGAACGGCGTCGCCATCCTGTACGCCGAC
AAAATTACCGACTCCATGAAAGCCGCCGTCGACGAAACCGAACGCCGCCGCGAAAAACAGATTAAATTCAACGAAGAACA
CGGTATCGTGCCGCAGCAGATTAAAAAACAGGTCAAAGACATCATCGACGGCGTGTACCACGAAGAAGACAGTGGCAAAG
GCCGTAGACAAGGCAAAAACAAGGTCAAAGTCGGCGAAATCCACAACGAAGAAGACGCGATTAAAGAAATCGCCAAACTG
GAAAAAGCCATGCAGCAGGCGGCTAGGGATTTACAGTTTGAAGAAGCTGCTGTGTTGAGGGATAGGATTAGGAATATTAA
AGAGAATTTGTTGTTTGGGGCGGAGTGA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

UvrB interaction domain (UvrB_inter)

(165-255)

Type III restriction enzyme, res subunit (ResIII)

(23-144)

UvrB/uvrC motif (UVR)

(635-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RMI9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.053

98.222

0.541
  uvrB Streptococcus pneumoniae R6

55.053

98.222

0.541
  uvrB Streptococcus pneumoniae D39

55.053

98.222

0.541