Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   EGH12_RS01315 Genome accession   NZ_CP034020
Coordinates   221888..222337 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   Q9JXJ2
Organism   Neisseria gonorrhoeae strain FQ48     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 216888..227337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH12_RS14035 (EGH12_01300) - 221184..221303 (+) 120 Protein_206 competence protein ComE -
  EGH12_RS01310 (EGH12_01310) comE 221405..221800 (+) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  EGH12_RS01315 (EGH12_01315) comP 221888..222337 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  EGH12_RS01325 (EGH12_01325) - 222714..222860 (-) 147 WP_003691757.1 hypothetical protein -
  EGH12_RS01330 (EGH12_01330) - 223247..223837 (+) 591 WP_080229150.1 DNA cytosine methyltransferase -
  EGH12_RS01335 (EGH12_01335) - 223834..224205 (+) 372 WP_012503918.1 DNA cytosine methyltransferase -
  EGH12_RS14040 - 224219..225076 (+) 858 WP_012503917.1 ATP-binding protein -
  EGH12_RS14045 - 225266..225862 (+) 597 WP_012503916.1 TIGR02391 family protein -
  EGH12_RS01345 (EGH12_01345) - 225868..226290 (+) 423 WP_003691751.1 very short patch repair endonuclease -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=287089 EGH12_RS01315 WP_002214937.1 221888..222337(+) (comP) [Neisseria gonorrhoeae strain FQ48]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=287089 EGH12_RS01315 WP_002214937.1 221888..222337(+) (comP) [Neisseria gonorrhoeae strain FQ48]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterProScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9JXJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49