Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   EHF39_RS09395 Genome accession   NZ_CP033908
Coordinates   1825452..1826048 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain RLGH     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1820452..1831048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF39_RS09360 (EHF39_09360) - 1820512..1820817 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  EHF39_RS09365 (EHF39_09365) ruvX 1820829..1821248 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EHF39_RS09370 (EHF39_09370) - 1821245..1821514 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EHF39_RS09375 (EHF39_09375) spx 1821628..1822026 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EHF39_RS09380 (EHF39_09380) recA 1822317..1823453 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  EHF39_RS09385 (EHF39_09385) cinA 1823542..1824813 (-) 1272 WP_002992182.1 competence/damage-inducible protein A Machinery gene
  EHF39_RS09390 (EHF39_09390) - 1824882..1825442 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  EHF39_RS09395 (EHF39_09395) ruvA 1825452..1826048 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  EHF39_RS09400 (EHF39_09400) - 1826050..1827270 (-) 1221 WP_011529098.1 MFS transporter -
  EHF39_RS09405 (EHF39_09405) hexB 1827281..1829263 (-) 1983 WP_021299132.1 DNA mismatch repair endonuclease MutL Machinery gene
  EHF39_RS09410 (EHF39_09410) - 1829358..1830509 (-) 1152 WP_003058754.1 site-specific integrase -
  EHF39_RS09415 (EHF39_09415) - 1830758..1830901 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=285962 EHF39_RS09395 WP_002992186.1 1825452..1826048(-) (ruvA) [Streptococcus pyogenes strain RLGH]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=285962 EHF39_RS09395 WP_002992186.1 1825452..1826048(-) (ruvA) [Streptococcus pyogenes strain RLGH]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment