Detailed information NTG0285902

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EHF39_RS02365
• Genome accession: NZ_CP033908
• Coordinates: 427858..428859 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain RLGH
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 422858..433859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHF39_RS02340 (EHF39_02340)	-	423532..424215 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
EHF39_RS02345 (EHF39_02345)	-	424426..425352 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
EHF39_RS02350 (EHF39_02350)	-	425497..425874 (-)	378	WP_002985686.1	VOC family protein	-
EHF39_RS02355 (EHF39_02355)	-	425885..426550 (-)	666	WP_121158073.1	NAD(P)H-dependent oxidoreductase	-
EHF39_RS02360 (EHF39_02360)	-	426599..427684 (-)	1086	WP_011528361.1	Xaa-Pro peptidase family protein	-
EHF39_RS02365 (EHF39_02365)	ccpA	427858..428859 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EHF39_RS02370 (EHF39_02370)	-	428990..429988 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EHF39_RS02375 (EHF39_02375)	-	429990..431324 (+)	1335	WP_011528362.1	glycosyltransferase family 4 protein	-
EHF39_RS02380 (EHF39_02380)	thrS	431746..433689 (+)	1944	WP_011528363.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=285902 EHF39_RS02365 WP_002985680.1 427858..428859(+) (ccpA) [Streptococcus pyogenes strain RLGH]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=285902 EHF39_RS02365 WP_002985680.1 427858..428859(+) (ccpA) [Streptococcus pyogenes strain RLGH]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559