Detailed information NTG0285827

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EHF40_RS06035
• Genome accession: NZ_CP033907
• Coordinates: 1141016..1143007 (-)
• Length: 663 a.a.
• NCBI ID: WP_011528712.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Duke-Large
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1136016..1148007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHF40_RS06010 (EHF40_06010)	dltD	1136305..1137555 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
EHF40_RS06015 (EHF40_06015)	dltC	1137548..1137787 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
EHF40_RS06020 (EHF40_06020)	dltB	1137805..1139061 (-)	1257	WP_002994626.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
EHF40_RS06025 (EHF40_06025)	dltA	1139058..1140596 (-)	1539	WP_011528711.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
EHF40_RS06030 (EHF40_06030)	-	1140608..1140751 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
EHF40_RS06035 (EHF40_06035)	uvrB	1141016..1143007 (-)	1992	WP_011528712.1	excinuclease ABC subunit UvrB	Machinery gene
EHF40_RS06040 (EHF40_06040)	-	1143199..1145373 (+)	2175	WP_002984191.1	ABC transporter substrate-binding protein/permease	-
EHF40_RS06045 (EHF40_06045)	-	1145373..1146113 (+)	741	WP_011528713.1	amino acid ABC transporter ATP-binding protein	-
EHF40_RS09905	-	1146261..1146413 (-)	153	WP_011528714.1	hypothetical protein	-
EHF40_RS06050 (EHF40_06050)	-	1146410..1147789 (-)	1380	WP_011528715.1	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75668.70 Da
• Isoelectric Point: 4.6420

>NTDB_id=285827 EHF40_RS06035 WP_011528712.1 1141016..1143007(-) (uvrB) [Streptococcus pyogenes strain Duke-Large]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGIFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=285827 EHF40_RS06035 WP_011528712.1 1141016..1143007(-) (uvrB) [Streptococcus pyogenes strain Duke-Large]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATACTTTGTTTCCTATTATGACTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGTCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTATTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

• UvrB interaction domain (UvrB_inter) (164-254)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.766	100	0.848
uvrB	Streptococcus pneumoniae D39	84.766	100	0.848
uvrB	Streptococcus pneumoniae TIGR4	84.615	100	0.846