Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   EGX80_RS04645 Genome accession   NZ_CP033815
Coordinates   870839..871435 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain FDAARGOS_514     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 865839..876435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX80_RS04610 (EGX80_04615) - 865900..866205 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  EGX80_RS04615 (EGX80_04620) ruvX 866217..866636 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EGX80_RS04620 (EGX80_04625) - 866633..866902 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EGX80_RS04625 (EGX80_04630) spx 867015..867413 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EGX80_RS04630 (EGX80_04635) recA 867704..868840 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  EGX80_RS04635 (EGX80_04640) cinA 868929..870200 (-) 1272 WP_011055089.1 competence/damage-inducible protein A Machinery gene
  EGX80_RS04640 (EGX80_04645) - 870269..870829 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  EGX80_RS04645 (EGX80_04650) ruvA 870839..871435 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  EGX80_RS04650 (EGX80_04655) - 871437..872657 (-) 1221 WP_011055090.1 MFS transporter -
  EGX80_RS04655 (EGX80_04660) hexB 872668..874650 (-) 1983 WP_002992189.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=284802 EGX80_RS04645 WP_002992186.1 870839..871435(-) (ruvA) [Streptococcus pyogenes strain FDAARGOS_514]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=284802 EGX80_RS04645 WP_002992186.1 870839..871435(-) (ruvA) [Streptococcus pyogenes strain FDAARGOS_514]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419