Detailed information NTG0284683

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SK637_RS01460
• Genome accession: NZ_CP028415
• Coordinates: 281782..282792 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090628.1
• Uniprot ID: F9HAD8
• Organism: Streptococcus mitis strain SK637
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 276782..287792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SK637_RS01435 (SK637_00283)	folP	277378..278352 (+)	975	WP_033688088.1	dihydropteroate synthase	-
SK637_RS01440 (SK637_00284)	-	278354..279676 (+)	1323	WP_033688089.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
SK637_RS01445 (SK637_00285)	folE	279657..280211 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
SK637_RS01450 (SK637_00286)	folB	280369..281181 (+)	813	WP_033688090.1	dihydroneopterin aldolase	-
SK637_RS01455 (SK637_00287)	-	281226..281543 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
SK637_RS01460 (SK637_00288)	ccpA	281782..282792 (+)	1011	WP_001090628.1	catabolite control protein A	Regulator
SK637_RS01465 (SK637_00289)	-	282846..283808 (-)	963	WP_033688092.1	asparaginase	-
SK637_RS01470 (SK637_00290)	-	283874..285265 (+)	1392	WP_033688093.1	Cof-type HAD-IIB family hydrolase	-
SK637_RS01475 (SK637_00291)	-	285412..285864 (-)	453	WP_000079148.1	universal stress protein	-
SK637_RS01480 (SK637_00292)	-	286026..286328 (+)	303	WP_033688094.1	hypothetical protein	-
SK637_RS01485 (SK637_00293)	-	286482..287696 (+)	1215	WP_033688095.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37155.16 Da
• Isoelectric Point: 5.3350

>NTDB_id=284683 SK637_RS01460 WP_001090628.1 281782..282792(+) (ccpA) [Streptococcus mitis strain SK637]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQVSRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=284683 SK637_RS01460 WP_001090628.1 281782..282792(+) (ccpA) [Streptococcus mitis strain SK637]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTGGATTACCGTCCAAATG
CCGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATCCCCAATATTACCAATGGTTATTTCTCA
ACGCTTGCTAAAGGAATTGATGATATCGCTGAAATGTACAAGTATAACATCGTCCTTGCTAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTGGTTAACACCCTGTTTTCTAAGCAAGTGGATGGTATCATTTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATTGATGCAGTAACCTACCTTGCTAAAGAGAACGAGCGCATTGCTTTCGTTAG
CGGTCCACTAGTGGATGACATCAATGGTAAGGTTCGCTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAATCTAAATACACTTATGAAGATGGCTATGCCTTGGCAGAGCGTTTAATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAACTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTATCAGTACC
AGAAGAGTTTGAAATTATTACTAGTGATGATTCGCAAGTCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGATTAACAGAACGTCGTTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: F9HAD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.238	100	0.952
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.222	99.405	0.887
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568