Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   SM12261_RS06745 Genome accession   NZ_CP028414
Coordinates   1305784..1307742 (-) Length   652 a.a.
NCBI ID   WP_000748522.1    Uniprot ID   A0AAX2L4A6
Organism   Streptococcus mitis NCTC 12261     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1300784..1312742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS06730 (SM12261_1308) - 1302583..1303749 (-) 1167 WP_000521355.1 MalY/PatB family protein -
  SM12261_RS06735 (SM12261_1309) - 1303757..1304851 (-) 1095 WP_000031982.1 cystathionine gamma-synthase -
  SM12261_RS06740 (SM12261_1310) - 1305016..1305471 (-) 456 WP_000500942.1 hypothetical protein -
  SM12261_RS06745 (SM12261_1311) amiA 1305784..1307742 (-) 1959 WP_000748522.1 peptide ABC transporter substrate-binding protein Regulator
  SM12261_RS06750 (SM12261_1312) - 1307947..1309570 (-) 1624 Protein_1222 putative polysaccharide biosynthesis protein -
  SM12261_RS06755 (SM12261_1313) - 1309676..1311121 (+) 1446 WP_000590269.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  SM12261_RS06760 (SM12261_1314) - 1311168..1311359 (-) 192 WP_000051184.1 CsbD family protein -
  SM12261_RS06765 (SM12261_1315) - 1311460..1312110 (-) 651 WP_000614491.1 DUF1803 domain-containing protein -
  SM12261_RS06770 (SM12261_1316) - 1312094..1312606 (-) 513 WP_000892239.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72553.85 Da        Isoelectric Point: 4.8984

>NTDB_id=284648 SM12261_RS06745 WP_000748522.1 1305784..1307742(-) (amiA) [Streptococcus mitis NCTC 12261]
MKKSKAKYAALAGVVLSAGILLSACGSSSTGSKTYNYVYTSDPSSLNYLAENRATTNDIVTNLVDGLMENDQYGNYIPSL
AEDWSVSKDGLTYTYKLRKDAKWYTADGEEYAPVTAQDFVTGLKYAADKKSEALYLVQESVAGLDDYINGKTSDFSTVGV
KALDDQTVQYTLTRPESYWNSKTTSTILFPVNADFLKSKGDDFGKVDPSSILYNGPFLMKSFVSKSVIEFKKNPNYWDAK
NVFVDDVKLAYYDGSDQDALARNFVEGAYSYARLYPNSASFEGIKEKNKDNIIYSLQDATSYFLNFNLDRKSYKFTSKTS
DAEKKSTQEAVLNKNFRQAINFAYDRTAYGAQSQGEDGATKILRNLVVPPNFVSINGKDFGEVVASKMVNYGKEWQGINF
ADAQDSYYNAEKAKAKFAEAKKELQAKGVQFPIHLDMTVDQAAKQGVQEANSMKQSIEAALGAENVVIDIQQLTTEDYDN
TSYLAQTAAQKDYDLYNGGWGPDYQDPSTYLDVFNLNSGGLLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDLAKR
YEKYADIQAWLVDSALAIPNVSKGGTPTLRKVVPFSTPYSLAGNKGIESYKYLKVQDKTVTKDEYEKAKEKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=284648 SM12261_RS06745 WP_000748522.1 1305784..1307742(-) (amiA) [Streptococcus mitis NCTC 12261]
ATGAAAAAGTCTAAAGCCAAGTATGCAGCACTTGCAGGTGTCGTGTTAAGTGCAGGTATTTTATTAAGCGCGTGTGGAAG
TTCTAGCACAGGGTCAAAAACATATAACTATGTTTATACCAGTGATCCGTCTAGTTTGAATTATCTAGCAGAAAACCGTG
CAACAACCAATGATATTGTGACTAATCTAGTAGATGGTCTCATGGAAAATGACCAGTATGGAAACTATATTCCATCTTTG
GCAGAGGATTGGAGTGTTTCTAAGGACGGTTTGACCTATACCTACAAACTGCGTAAAGATGCTAAATGGTATACTGCAGA
TGGAGAAGAATATGCTCCTGTAACTGCCCAAGATTTTGTAACTGGTTTGAAATATGCAGCAGATAAAAAATCAGAAGCCT
TGTACTTAGTTCAAGAATCCGTTGCAGGTTTGGATGATTACATTAACGGTAAAACAAGCGACTTTTCAACTGTCGGAGTC
AAGGCACTTGATGACCAAACTGTTCAATATACCTTGACACGACCAGAATCTTACTGGAACTCAAAAACAACTTCAACCAT
TCTCTTCCCAGTCAATGCGGATTTCTTGAAATCAAAAGGGGATGATTTTGGGAAGGTAGACCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAATCCTTTGTTTCAAAATCTGTTATTGAATTTAAGAAAAATCCGAACTACTGGGATGCTAAA
AATGTCTTTGTAGATGATGTGAAATTGGCTTATTATGATGGTAGTGACCAAGATGCACTAGCTCGTAACTTTGTTGAGGG
AGCTTATAGTTATGCTCGCCTTTATCCAAATAGTGCAAGCTTTGAAGGTATTAAAGAAAAGAATAAGGACAATATCATCT
ATAGCTTGCAAGATGCCACTTCTTATTTCTTAAACTTTAATCTAGATAGAAAATCTTATAAGTTCACTTCCAAGACAAGT
GATGCTGAAAAGAAATCGACTCAGGAAGCGGTTCTCAATAAAAACTTCCGTCAAGCCATTAACTTTGCCTATGATCGTAC
AGCTTACGGGGCTCAATCTCAGGGAGAAGATGGTGCAACTAAGATTTTGCGTAACTTGGTTGTTCCTCCAAACTTCGTAA
GTATCAACGGGAAAGACTTTGGTGAAGTAGTAGCCTCTAAGATGGTGAATTATGGTAAGGAATGGCAAGGAATCAACTTT
GCGGATGCCCAAGATTCATACTACAATGCTGAAAAAGCCAAGGCTAAATTTGCAGAGGCTAAGAAAGAACTCCAAGCTAA
AGGAGTCCAATTCCCTATTCACTTGGACATGACAGTTGACCAAGCTGCTAAACAGGGTGTTCAAGAGGCAAATTCTATGA
AGCAATCTATTGAAGCAGCTTTAGGTGCAGAAAATGTTGTAATTGATATTCAACAACTTACTACTGAAGACTATGATAAT
ACAAGCTATTTGGCTCAGACAGCAGCTCAGAAGGATTATGATCTATACAACGGTGGTTGGGGTCCTGATTACCAAGATCC
TTCAACCTATCTTGATGTCTTCAATCTTAATTCTGGTGGTTTGTTGCAAAATCTAGGTTTAGAGCCAGGTGAAGCCAATG
ACAAAGCCAAGGCTGTTGGATTGGATGTCTACACTCAAATGTTAGAAGAAGCCAATAAGGAACAAGATCTTGCAAAACGC
TATGAAAAGTATGCTGATATCCAAGCGTGGTTAGTAGATAGCGCTTTAGCGATTCCAAATGTTTCTAAGGGTGGAACACC
AACATTGAGAAAAGTTGTTCCTTTCTCAACACCATATTCATTAGCTGGTAATAAAGGTATCGAATCATATAAATATCTCA
AAGTACAAGATAAAACAGTCACAAAAGATGAATATGAAAAAGCCAAAGAAAAATGGCTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

57.751

100

0.583
  amiA3 Streptococcus thermophilus LMG 18311

56.904

100

0.575
  amiA3 Streptococcus thermophilus LMD-9

56.601

100

0.572

Multiple sequence alignment