Detailed information NTG0284477

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C9888_RS18590
• Genome accession: NZ_CP028375
• Coordinates: 3687374..3688537 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain W1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3682374..3693537

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9888_RS18560	-	3682639..3683058 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
C9888_RS18565	comFC	3683132..3683821 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
C9888_RS18570	-	3683827..3684111 (-)	285	WP_014419011.1	competence protein ComFB	-
C9888_RS18575	comFA	3684169..3685554 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
C9888_RS18580	-	3685662..3686510 (-)	849	WP_003151387.1	DegV family protein	-
C9888_RS18585	degU	3686608..3687297 (-)	690	WP_111927758.1	two-component system response regulator DegU	Regulator
C9888_RS18590	degS	3687374..3688537 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
C9888_RS18595	-	3688768..3689415 (+)	648	WP_007614107.1	YigZ family protein	-
C9888_RS18600	-	3689420..3690634 (+)	1215	WP_014419013.1	LCP family protein	-
C9888_RS18605	-	3690724..3691800 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
C9888_RS18610	-	3691933..3693129 (-)	1197	WP_014419014.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=284477 C9888_RS18590 WP_007407484.1 3687374..3688537(-) (degS) [Bacillus velezensis strain W1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=284477 C9888_RS18590 WP_007407484.1 3687374..3688537(-) (degS) [Bacillus velezensis strain W1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951