Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EEL45_RS24715 Genome accession   NZ_CP033605
Coordinates   4738018..4738608 (-) Length   196 a.a.
NCBI ID   WP_005016525.1    Uniprot ID   Q329E6
Organism   Escherichia coli O157:H7 strain TR01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4733018..4743608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EEL45_RS24700 (EEL45_24700) uhpT 4733658..4735049 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EEL45_RS24705 (EEL45_24705) uhpC 4735187..4736506 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EEL45_RS24710 (EEL45_24710) uhpB 4736516..4738018 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EEL45_RS24715 (EEL45_24715) letA 4738018..4738608 (-) 591 WP_005016525.1 transcriptional regulator UhpA Regulator
  EEL45_RS24725 (EEL45_24725) - 4738769..4739872 (-) 1104 WP_123178723.1 hypothetical protein -
  EEL45_RS24735 (EEL45_24735) - 4740482..4741765 (-) 1284 WP_123178724.1 hypothetical protein -
  EEL45_RS24740 (EEL45_24740) ilvN 4742029..4742319 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20917.36 Da        Isoelectric Point: 5.9982

>NTDB_id=283707 EEL45_RS24715 WP_005016525.1 4738018..4738608(-) (letA) [Escherichia coli O157:H7 strain TR01]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIVAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=283707 EEL45_RS24715 WP_005016525.1 4738018..4738608(-) (letA) [Escherichia coli O157:H7 strain TR01]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGTTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATTTCCGGTCTGGAACTGCTAAGCCAACTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTTTCCAAACGCTGTAGCCCTGACGA
ACTGATTGTTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q329E6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38

100

0.388
  letA Legionella pneumophila strain ERS1305867

38

100

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378