Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EEL45_RS22660 Genome accession   NZ_CP033605
Coordinates   4307185..4307817 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O157:H7 strain TR01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4302185..4312817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EEL45_RS22635 (EEL45_22635) yheS 4302354..4304267 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EEL45_RS22640 (EEL45_22640) yheT 4304267..4305289 (+) 1023 WP_000057379.1 hydrolase -
  EEL45_RS22645 (EEL45_22645) yheU 4305283..4305501 (+) 219 WP_000907085.1 YheU family protein -
  EEL45_RS22650 (EEL45_22650) prkB 4305555..4306424 (+) 870 WP_001274680.1 phosphoribulokinase -
  EEL45_RS22655 (EEL45_22655) yhfA 4306479..4306883 (-) 405 WP_001148908.1 OsmC family protein -
  EEL45_RS22660 (EEL45_22660) crp 4307185..4307817 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EEL45_RS22665 (EEL45_22665) yhfK 4307868..4309958 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EEL45_RS22670 (EEL45_22670) argD 4310025..4311245 (-) 1221 WP_000963810.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EEL45_RS22675 (EEL45_22675) pabA 4311331..4311894 (-) 564 WP_000601848.1 aminodeoxychorismate synthase component 2 -
  EEL45_RS22680 (EEL45_22680) fic 4311926..4312528 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EEL45_RS22685 (EEL45_22685) yhfG 4312518..4312685 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=283699 EEL45_RS22660 WP_000242755.1 4307185..4307817(+) (crp) [Escherichia coli O157:H7 strain TR01]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=283699 EEL45_RS22660 WP_000242755.1 4307185..4307817(+) (crp) [Escherichia coli O157:H7 strain TR01]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAAATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467