Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EEL45_RS13105 Genome accession   NZ_CP033605
Coordinates   2523805..2524461 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O157:H7 strain TR01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2518805..2529461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EEL45_RS29170 (EEL45_13065) - 2519774..2519941 (-) 168 Protein_2521 hypothetical protein -
  EEL45_RS13070 (EEL45_13070) - 2519883..2520077 (-) 195 WP_115801851.1 hypothetical protein -
  EEL45_RS13075 (EEL45_13075) - 2520098..2520379 (-) 282 WP_001303543.1 hypothetical protein -
  EEL45_RS13095 (EEL45_13095) pgsA 2521371..2521919 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EEL45_RS13100 (EEL45_13100) uvrC 2521976..2523808 (-) 1833 WP_096266103.1 excinuclease ABC subunit UvrC Machinery gene
  EEL45_RS13105 (EEL45_13105) letA 2523805..2524461 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EEL45_RS13110 (EEL45_13110) yecU 2524757..2524933 (+) 177 WP_001307856.1 protein YecU -
  EEL45_RS13115 (EEL45_13115) yecF 2524920..2525144 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EEL45_RS13120 (EEL45_13120) sdiA 2525212..2525934 (-) 723 WP_024231281.1 transcriptional regulator SdiA -
  EEL45_RS13125 (EEL45_13125) tcyN 2526164..2526916 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EEL45_RS13130 (EEL45_13130) tcyL 2526913..2527581 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EEL45_RS13135 (EEL45_13135) dcyD 2527596..2528582 (-) 987 WP_025652951.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=283673 EEL45_RS13105 WP_000611328.1 2523805..2524461(-) (letA) [Escherichia coli O157:H7 strain TR01]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=283673 EEL45_RS13105 WP_000611328.1 2523805..2524461(-) (letA) [Escherichia coli O157:H7 strain TR01]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482