Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EEL45_RS13100 Genome accession   NZ_CP033605
Coordinates   2521976..2523808 (-) Length   610 a.a.
NCBI ID   WP_096266103.1    Uniprot ID   -
Organism   Escherichia coli O157:H7 strain TR01     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2516976..2528808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EEL45_RS13050 (EEL45_13050) - 2517218..2517484 (+) 267 Protein_2518 phage late control D family protein -
  EEL45_RS13055 (EEL45_13055) - 2517492..2518466 (-) 975 Protein_2519 IS30-like element IS30 family transposase -
  EEL45_RS13060 (EEL45_13060) - 2518518..2519731 (+) 1214 WP_162829242.1 IS3 family transposase -
  EEL45_RS29170 (EEL45_13065) - 2519774..2519941 (-) 168 Protein_2521 hypothetical protein -
  EEL45_RS13070 (EEL45_13070) - 2519883..2520077 (-) 195 WP_115801851.1 hypothetical protein -
  EEL45_RS13075 (EEL45_13075) - 2520098..2520379 (-) 282 WP_001303543.1 hypothetical protein -
  EEL45_RS13095 (EEL45_13095) pgsA 2521371..2521919 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EEL45_RS13100 (EEL45_13100) uvrC 2521976..2523808 (-) 1833 WP_096266103.1 excinuclease ABC subunit UvrC Machinery gene
  EEL45_RS13105 (EEL45_13105) letA 2523805..2524461 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EEL45_RS13110 (EEL45_13110) yecU 2524757..2524933 (+) 177 WP_001307856.1 protein YecU -
  EEL45_RS13115 (EEL45_13115) yecF 2524920..2525144 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EEL45_RS13120 (EEL45_13120) sdiA 2525212..2525934 (-) 723 WP_024231281.1 transcriptional regulator SdiA -
  EEL45_RS13125 (EEL45_13125) tcyN 2526164..2526916 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EEL45_RS13130 (EEL45_13130) tcyL 2526913..2527581 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EEL45_RS13135 (EEL45_13135) dcyD 2527596..2528582 (-) 987 WP_025652951.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68228.10 Da        Isoelectric Point: 9.3716

>NTDB_id=283672 EEL45_RS13100 WP_096266103.1 2521976..2523808(-) (uvrC) [Escherichia coli O157:H7 strain TR01]
MSDQFDAKAFLRTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHIMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=283672 EEL45_RS13100 WP_096266103.1 2521976..2523808(-) (uvrC) [Escherichia coli O157:H7 strain TR01]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAGAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCAAAGCATGCCAAAGGTGAATATTTCGGCCCGTTTCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCATGTCTGCAATATCAGATAGGGCGCTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGTCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATATCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCTGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGCTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGCTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.056

99.508

0.379
  uvrC Streptococcus pneumoniae R6

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae D39

37.727

99.508

0.375