Detailed information NTG0283147

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C7M27_RS00315
• Genome accession: NZ_CP028213
• Coordinates: 71790..72947 (+)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain SRCM102749
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 66790..77947

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M27_RS00295 (C7M27_00059)	tuaH	67258..68451 (+)	1194	WP_103803439.1	glycosyltransferase family 1 protein	-
C7M27_RS00300 (C7M27_00060)	tagO	68596..69672 (+)	1077	WP_003227975.1	MraY family glycosyltransferase	-
C7M27_RS00305 (C7M27_00061)	tagV	69745..70920 (-)	1176	WP_103803401.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
C7M27_RS00310 (C7M27_00062)	yvyE	70920..71573 (-)	654	WP_003227979.1	YigZ family protein	-
C7M27_RS00315 (C7M27_00063)	degS	71790..72947 (+)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
C7M27_RS00320 (C7M27_00064)	degU	73030..73719 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
C7M27_RS00325 (C7M27_00065)	fakBA	73817..74662 (+)	846	WP_003227986.1	DegV family protein	-
C7M27_RS00330 (C7M27_00066)	comFA	74770..76161 (+)	1392	WP_128740769.1	ATP-dependent helicase ComFA	Machinery gene
C7M27_RS00335 (C7M27_00067)	comFB	76221..76517 (+)	297	WP_003227989.1	late competence protein ComFB	-
C7M27_RS00340 (C7M27_00068)	comFC	76481..77203 (+)	723	WP_124047882.1	comF operon protein ComFC	Machinery gene
C7M27_RS00345 (C7M27_00069)	yvyF	77277..77696 (+)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=283147 C7M27_RS00315 WP_003227983.1 71790..72947(+) (degS) [Bacillus subtilis strain SRCM102749]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=283147 C7M27_RS00315 WP_003227983.1 71790..72947(+) (degS) [Bacillus subtilis strain SRCM102749]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTAAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGGTCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1