Detailed information NTG0283087

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EB817_RS04220
• Genome accession: NZ_CP033336
• Coordinates: 798089..800080 (+)
• Length: 663 a.a.
• NCBI ID: WP_129304652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY165
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 793089..805080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB817_RS04205 (EB817_04210)	-	793306..794685 (+)	1380	WP_129304650.1	PTS transporter subunit EIIC	-
EB817_RS09270	-	794682..794834 (+)	153	WP_003062002.1	hypothetical protein	-
EB817_RS04210 (EB817_04215)	-	794982..795722 (-)	741	WP_012560768.1	amino acid ABC transporter ATP-binding protein	-
EB817_RS04215 (EB817_04220)	-	795722..797896 (-)	2175	WP_002989566.1	ABC transporter substrate-binding protein/permease	-
EB817_RS04220 (EB817_04225)	uvrB	798089..800080 (+)	1992	WP_129304652.1	excinuclease ABC subunit UvrB	Machinery gene
EB817_RS04225 (EB817_04230)	-	800343..800486 (+)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
EB817_RS04230 (EB817_04235)	dltA	800498..802036 (+)	1539	WP_129304654.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
EB817_RS04235 (EB817_04240)	dltB	802033..803289 (+)	1257	WP_129304656.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
EB817_RS04240 (EB817_04245)	dltC	803307..803546 (+)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
EB817_RS04245 (EB817_04250)	dltD	803539..804789 (+)	1251	WP_129304658.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75676.77 Da
• Isoelectric Point: 4.6420

>NTDB_id=283087 EB817_RS04220 WP_129304652.1 798089..800080(+) (uvrB) [Streptococcus pyogenes strain TSPY165]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKII
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=283087 EB817_RS04220 WP_129304652.1 798089..800080(+) (uvrB) [Streptococcus pyogenes strain TSPY165]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCTTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAATTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCGAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• UvrB interaction domain (UvrB_inter) (164-254)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB/uvrC motif (UVR) (627-660)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	85.068	100	0.851
uvrB	Streptococcus pneumoniae D39	85.068	100	0.851
uvrB	Streptococcus pneumoniae TIGR4	84.917	100	0.849