Detailed information NTG0282777

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C7M22_RS04420
• Genome accession: NZ_CP028208
• Coordinates: 860009..861172 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SRCM102744
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 855009..866172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M22_RS04390 (C7M22_00882)	-	855273..855692 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
C7M22_RS04395	comFC	855766..856455 (-)	690	WP_197200179.1	phosphoribosyltransferase family protein	Machinery gene
C7M22_RS04400 (C7M22_00884)	-	856461..856745 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
C7M22_RS04405 (C7M22_00885)	comFA	856803..858188 (-)	1386	WP_160223300.1	DEAD/DEAH box helicase	Machinery gene
C7M22_RS04410 (C7M22_00886)	-	858297..859145 (-)	849	WP_003151387.1	DegV family protein	-
C7M22_RS04415 (C7M22_00887)	degU	859243..859932 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
C7M22_RS04420 (C7M22_00888)	degS	860009..861172 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
C7M22_RS04425 (C7M22_00889)	-	861395..862042 (+)	648	WP_061581228.1	YigZ family protein	-
C7M22_RS04430 (C7M22_00890)	-	862047..863267 (+)	1221	WP_160223301.1	LCP family protein	-
C7M22_RS04435 (C7M22_00891)	-	863366..864442 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
C7M22_RS04440 (C7M22_00892)	tuaH	864575..865771 (-)	1197	WP_069006925.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=282777 C7M22_RS04420 WP_007407484.1 860009..861172(-) (degS) [Bacillus velezensis strain SRCM102744]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=282777 C7M22_RS04420 WP_007407484.1 860009..861172(-) (degS) [Bacillus velezensis strain SRCM102744]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTTGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951