Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EAF06_RS11640 Genome accession   NZ_CP033158
Coordinates   2438005..2438595 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CM IVRI KOL-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2433005..2443595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAF06_RS11625 (EAF06_12030) uhpT 2433645..2435036 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EAF06_RS11630 (EAF06_12035) uhpC 2435174..2436493 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EAF06_RS11635 (EAF06_12040) uhpB 2436503..2438005 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EAF06_RS11640 (EAF06_12045) letA 2438005..2438595 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EAF06_RS11645 (EAF06_12050) ilvN 2438670..2438960 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EAF06_RS11650 (EAF06_12055) ilvB 2438964..2440652 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  EAF06_RS11655 (EAF06_12060) ivbL 2440758..2440856 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  EAF06_RS11660 (EAF06_12070) - 2441248..2442468 (+) 1221 WP_000343760.1 ISL3-like element ISKox3 family transposase -
  EAF06_RS11665 (EAF06_12080) tisB 2442745..2442834 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  EAF06_RS25085 ysdE 2442958..2443032 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=282453 EAF06_RS11640 WP_000633668.1 2438005..2438595(-) (letA) [Escherichia coli strain CM IVRI KOL-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=282453 EAF06_RS11640 WP_000633668.1 2438005..2438595(-) (letA) [Escherichia coli strain CM IVRI KOL-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment