Detailed information NTG0028233

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: LPC_RS07955
• Genome accession: NC_009494
• Coordinates: 1753379..1754242 (+)
• Length: 287 a.a.
• NCBI ID: WP_011946525.1
• Uniprot ID: I7HJU8
• Organism: Legionella pneumophila str. Corby
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1748379..1759242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPC_RS07935 (LPC_0939)	-	1748872..1749198 (-)	327	WP_011213802.1	DUF1820 family protein	-
LPC_RS07940 (LPC_0940)	-	1749381..1750124 (-)	744	WP_011213803.1	methyltransferase domain-containing protein	-
LPC_RS07945 (LPC_0941)	pilB	1750383..1752107 (+)	1725	WP_011946523.1	type IV-A pilus assembly ATPase PilB	Machinery gene
LPC_RS07950 (LPC_0942)	pilC	1752113..1753333 (+)	1221	WP_011946524.1	type II secretion system F family protein	Machinery gene
LPC_RS07955 (LPC_0943)	pilD	1753379..1754242 (+)	864	WP_011946525.1	prepilin peptidase	Machinery gene
LPC_RS07960 (LPC_0944)	-	1754256..1754687 (-)	432	WP_011946526.1	CPBP family intramembrane glutamic endopeptidase	-
LPC_RS07965	-	1754713..1755534 (-)	822	WP_228370635.1	IS982 family transposase	-
LPC_RS07970 (LPC_0946)	-	1755686..1756486 (-)	801	WP_011946527.1	cyclic nucleotide-binding domain-containing protein	-
LPC_RS07975 (LPC_0947)	-	1756594..1757187 (-)	594	WP_011946528.1	hypothetical protein	-
LPC_RS07980 (LPC_0948)	-	1757203..1757658 (-)	456	WP_011946529.1	hypothetical protein	-
LPC_RS07985 (LPC_0949)	-	1757792..1758607 (+)	816	WP_010947257.1	pyruvate, water dikinase regulatory protein	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 32800.45 Da
• Isoelectric Point: 7.8327

>NTDB_id=28233 LPC_RS07955 WP_011946525.1 1753379..1754242(+) (pilD) [Legionella pneumophila str. Corby]
MINALIINYPWFMYLVVGLFSLAVGSLLNVIIYRLPIILQEEWKEQCCELFQLEQRKEKIKLNLFLPRSFCPHCKAMVKA
WQNIPLLSYILLRGRCYQCDSPISIRYPFVETLTTVLSLYASWHFGFTIQLLFALLAIWILISLVFIDLDHQLLPDSLTL
GLLWIGLIANTQNIFVSLDVAVLSCAGAYLALWLFINLFYLMTGKVGMGHGDFKLFAAFGAWLGWMYLPLILLISSITGA
IIGLIYLKINGKSRDTAIPFGPFLCISGLIAMFWGDLIINWYIGYWM

Nucleotide

• Length: 864 bp

>NTDB_id=28233 LPC_RS07955 WP_011946525.1 1753379..1754242(+) (pilD) [Legionella pneumophila str. Corby]
ATGATAAATGCACTAATAATCAATTATCCATGGTTTATGTATTTAGTCGTTGGACTCTTTTCTCTAGCTGTTGGAAGTTT
GCTTAATGTGATAATCTATCGCTTACCAATTATTTTGCAGGAAGAGTGGAAAGAGCAATGCTGTGAGCTATTCCAGCTTG
AACAGCGAAAAGAAAAAATAAAACTTAATTTATTTTTACCACGTTCTTTTTGCCCTCATTGTAAAGCGATGGTTAAAGCG
TGGCAGAATATTCCTCTGTTAAGCTATATTTTGTTAAGAGGACGCTGTTACCAATGCGATAGTCCAATTTCAATTCGCTA
CCCTTTTGTTGAGACTCTGACCACAGTTTTATCCTTATACGCCAGTTGGCATTTTGGGTTTACAATACAACTATTATTTG
CTTTATTAGCTATCTGGATATTAATATCACTTGTTTTTATTGATCTTGATCATCAATTACTCCCTGATAGCCTCACTTTA
GGGCTCTTATGGATTGGCCTCATTGCTAATACCCAGAATATATTTGTTAGTCTTGACGTTGCTGTATTAAGCTGCGCTGG
CGCCTATTTAGCCTTATGGTTATTCATTAATCTGTTTTATCTGATGACAGGTAAAGTAGGTATGGGACATGGGGATTTCA
AATTATTTGCAGCATTTGGTGCATGGCTTGGATGGATGTATTTACCATTAATTCTACTAATATCTTCAATAACCGGGGCT
ATCATTGGTTTGATTTATTTAAAGATAAATGGTAAATCAAGAGATACTGCAATACCATTTGGCCCTTTTCTTTGCATTTC
TGGATTAATAGCTATGTTTTGGGGAGATTTAATTATCAATTGGTATATAGGTTATTGGATGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (19-125)

• Type IV leader peptidase family (Peptidase_A24) (136-244)

3D structure

• AlphaFold DB: I7HJU8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.11	97.909	0.481
pilD	Acinetobacter nosocomialis M2	48.352	95.122	0.46
pilD	Acinetobacter baumannii D1279779	47.636	95.819	0.456
pilD	Vibrio campbellii strain DS40M4	45.683	96.864	0.443
pilD	Neisseria gonorrhoeae MS11	42.446	96.864	0.411