Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LPC_RS07950 Genome accession   NC_009494
Coordinates   1752113..1753333 (+) Length   406 a.a.
NCBI ID   WP_011946524.1    Uniprot ID   -
Organism   Legionella pneumophila str. Corby     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1747113..1758333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC_RS07930 (LPC_0938) - 1748260..1748829 (-) 570 WP_011213801.1 hypoxanthine-guanine phosphoribosyltransferase -
  LPC_RS07935 (LPC_0939) - 1748872..1749198 (-) 327 WP_011213802.1 DUF1820 family protein -
  LPC_RS07940 (LPC_0940) - 1749381..1750124 (-) 744 WP_011213803.1 methyltransferase domain-containing protein -
  LPC_RS07945 (LPC_0941) pilB 1750383..1752107 (+) 1725 WP_011946523.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LPC_RS07950 (LPC_0942) pilC 1752113..1753333 (+) 1221 WP_011946524.1 type II secretion system F family protein Machinery gene
  LPC_RS07955 (LPC_0943) pilD 1753379..1754242 (+) 864 WP_011946525.1 prepilin peptidase Machinery gene
  LPC_RS07960 (LPC_0944) - 1754256..1754687 (-) 432 WP_011946526.1 CPBP family intramembrane glutamic endopeptidase -
  LPC_RS07965 - 1754713..1755534 (-) 822 WP_228370635.1 IS982 family transposase -
  LPC_RS07970 (LPC_0946) - 1755686..1756486 (-) 801 WP_011946527.1 cyclic nucleotide-binding domain-containing protein -
  LPC_RS07975 (LPC_0947) - 1756594..1757187 (-) 594 WP_011946528.1 hypothetical protein -
  LPC_RS07980 (LPC_0948) - 1757203..1757658 (-) 456 WP_011946529.1 hypothetical protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44719.92 Da        Isoelectric Point: 9.6052

>NTDB_id=28232 LPC_RS07950 WP_011946524.1 1752113..1753333(+) (pilC) [Legionella pneumophila str. Corby]
MDKNSPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGIVYSF
FYAKNHSLEFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFIAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=28232 LPC_RS07950 WP_011946524.1 1752113..1753333(+) (pilC) [Legionella pneumophila str. Corby]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAGTAAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACTGTATTTAGCCGCCAATTAGCGACGATGATC
GAGTCTGGAATACCATTAGTGCAAGCGTTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTAGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGTGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTATCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
GGGATTATTAATCTATGTGGTTCCTCAATTTGAATCATTGTTTAAAGGATTTGGAGCTGACTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAGCTTTGGGTGGGATTGTCTATAGCTTT
TTTTATGCTAAAAATCACTCTTTGGAATTTGCTCAAACTATTGACAGAGTGATGCTAAAATTCCCTGTAATTGGCCCTAT
TTTAGAGAAAGCAGCAATTGCTCGATTTGCGAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACCGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGGGAAGAAGTTGCAACAGGA
CAGCAAATGTTTATTGCTATGGAAAACACTCATTTATTTCCGAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTAAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.507

100

0.995
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.333

99.754

0.532
  pilC Acinetobacter baylyi ADP1

52.84

99.754

0.527
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42.25

98.522

0.416
  pilC Vibrio campbellii strain DS40M4

39.163

100

0.392

Multiple sequence alignment