Detailed information NTG0282074

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: SAST44_RS03830
• Genome accession: NZ_CP033112
• Coordinates: 813402..815387 (+)
• Length: 661 a.a.
• NCBI ID: WP_000229253.1
• Uniprot ID: A0A0H2XGZ8
• Organism: Staphylococcus aureus strain ST20130944
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 808402..820387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST44_RS03815 (SAST44_03342)	-	811237..812076 (+)	840	WP_000749385.1	CHAP domain-containing protein	-
SAST44_RS03820 (SAST44_00846)	-	812250..812900 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
SAST44_RS03825 (SAST44_03086)	-	812897..813133 (+)	237	WP_000638419.1	CsbA family protein	-
SAST44_RS03830 (SAST44_00848)	uvrB	813402..815387 (+)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
SAST44_RS03835 (SAST44_04159)	uvrA	815395..818241 (+)	2847	WP_000662687.1	excinuclease ABC subunit UvrA	Machinery gene
SAST44_RS03840 (SAST44_00851)	hprK	818852..819784 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 76648.34 Da
• Isoelectric Point: 5.0538

>NTDB_id=282074 SAST44_RS03830 WP_000229253.1 813402..815387(+) (uvrB) [Staphylococcus aureus strain ST20130944]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide

• Length: 1986 bp

>NTDB_id=282074 SAST44_RS03830 WP_000229253.1 813402..815387(+) (uvrB) [Staphylococcus aureus strain ST20130944]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTTGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATTCGAGAAGTTAACTACCTAACTGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTACCGAGTGCAT
TAGATAACCGTCCTCTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (434-546)

• Ultra-violet resistance protein B (UvrB) (553-594)

• Type III restriction enzyme, res subunit (ResIII) (14-140)

• UvrB/uvrC motif (UVR) (626-659)

• UvrB interaction domain (UvrB_inter) (161-251)

3D structure

• AlphaFold DB: A0A0H2XGZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae TIGR4	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae D39	67.534	98.79	0.667