Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EAH50_RS04070 Genome accession   NZ_CP033096
Coordinates   428403..429035 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CP53     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 423403..434035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAH50_RS04045 (EAH50_04095) yhfG 423535..423702 (+) 168 WP_000736862.1 YhfG family protein -
  EAH50_RS04050 (EAH50_04100) fic 423692..424294 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EAH50_RS04055 (EAH50_04105) pabA 424326..424889 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EAH50_RS04060 (EAH50_04110) argD 424975..426195 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EAH50_RS04065 (EAH50_04115) yhfK 426262..428352 (-) 2091 WP_122056821.1 YccS/YhfK family putative transporter -
  EAH50_RS04070 (EAH50_04120) crp 428403..429035 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EAH50_RS04075 (EAH50_04130) yhfA 429337..429741 (+) 405 WP_122056822.1 OsmC family protein -
  EAH50_RS04080 (EAH50_04135) prkB 429796..430665 (-) 870 WP_001274680.1 phosphoribulokinase -
  EAH50_RS04085 (EAH50_04140) yheU 430719..430937 (-) 219 WP_000907085.1 YheU family protein -
  EAH50_RS04090 (EAH50_04145) yheT 430931..431953 (-) 1023 WP_000057356.1 hydrolase -
  EAH50_RS04095 (EAH50_04150) yheS 431953..433866 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=281836 EAH50_RS04070 WP_000242755.1 428403..429035(-) (crp) [Escherichia coli strain CP53]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=281836 EAH50_RS04070 WP_000242755.1 428403..429035(-) (crp) [Escherichia coli strain CP53]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment