Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EAS44_RS02655 Genome accession   NZ_CP033092
Coordinates   400535..401167 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 395535..406167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAS44_RS02630 (EAS44_18150) yhfG 395667..395834 (+) 168 WP_000736858.1 YhfG family protein -
  EAS44_RS02635 (EAS44_18155) fic 395824..396426 (+) 603 WP_001280656.1 putative adenosine monophosphate-protein transferase Fic -
  EAS44_RS02640 (EAS44_18160) pabA 396458..397021 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  EAS44_RS02645 (EAS44_18165) argD 397107..398327 (+) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EAS44_RS02650 (EAS44_18170) yhfK 398394..400484 (-) 2091 WP_025856754.1 YccS/YhfK family putative transporter -
  EAS44_RS02655 (EAS44_18175) crp 400535..401167 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EAS44_RS02660 (EAS44_18185) yhfA 401469..401873 (+) 405 WP_001148908.1 OsmC family protein -
  EAS44_RS02665 (EAS44_18190) prkB 401928..402797 (-) 870 WP_001274684.1 phosphoribulokinase -
  EAS44_RS02670 (EAS44_18195) yheU 402851..403069 (-) 219 WP_000907086.1 YheU family protein -
  EAS44_RS02675 (EAS44_18200) yheT 403063..404085 (-) 1023 WP_000057415.1 hydrolase -
  EAS44_RS02680 (EAS44_18205) yheS 404085..405998 (-) 1914 WP_000634747.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=281748 EAS44_RS02655 WP_000242755.1 400535..401167(-) (crp) [Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=281748 EAS44_RS02655 WP_000242755.1 400535..401167(-) (crp) [Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment