Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EAS44_RS00945 Genome accession   NZ_CP033092
Coordinates   28552..29142 (+) Length   196 a.a.
NCBI ID   WP_025856604.1    Uniprot ID   -
Organism   Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23552..34142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAS44_RS00915 (EAS44_16400) yidG 23844..24206 (+) 363 WP_001113443.1 DUF202 domain-containing protein -
  EAS44_RS00920 (EAS44_16405) yidF 24203..24700 (+) 498 WP_000148034.1 radical SAM protein -
  EAS44_RS00925 (EAS44_16410) emrD 24708..25892 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  EAS44_RS25300 ysdE 25974..26048 (+) 75 WP_211180519.1 protein YsdE -
  EAS44_RS00930 (EAS44_16415) ivbL 26293..26391 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  EAS44_RS00935 (EAS44_16420) ilvB 26497..28185 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  EAS44_RS00940 (EAS44_16425) ilvN 28189..28479 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EAS44_RS00945 (EAS44_16430) letA 28552..29142 (+) 591 WP_025856604.1 transcriptional regulator UhpA Regulator
  EAS44_RS00950 (EAS44_16435) uhpB 29142..30644 (+) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EAS44_RS00955 (EAS44_16440) uhpC 30654..31973 (+) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EAS44_RS00960 (EAS44_16445) uhpT 32111..33502 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20852.25 Da        Isoelectric Point: 5.6059

>NTDB_id=281739 EAS44_RS00945 WP_025856604.1 28552..29142(+) (letA) [Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDISIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=281739 EAS44_RS00945 WP_025856604.1 28552..29142(+) (letA) [Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTTCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38

100

0.388
  letA Legionella pneumophila strain ERS1305867

38

100

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378