Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D9V56_RS00180 Genome accession   NZ_CP032986
Coordinates   33512..34102 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain BE2-5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28512..39102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9V56_RS00140 yidF 28627..29124 (+) 498 WP_121689802.1 radical SAM protein -
  D9V56_RS00145 emrD 29132..30316 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  D9V56_RS24120 ysdE 30398..30472 (+) 75 WP_211180519.1 protein YsdE -
  D9V56_RS00150 tisB 30596..30685 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  D9V56_RS00165 ivbL 31250..31348 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  D9V56_RS00170 ilvB 31454..33142 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  D9V56_RS00175 ilvN 33146..33436 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  D9V56_RS00180 letA 33512..34102 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  D9V56_RS00185 uhpB 34102..35604 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  D9V56_RS00190 uhpC 35614..36933 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  D9V56_RS00195 uhpT 37071..38462 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=281244 D9V56_RS00180 WP_000633668.1 33512..34102(+) (letA) [Escherichia coli strain BE2-5]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=281244 D9V56_RS00180 WP_000633668.1 33512..34102(+) (letA) [Escherichia coli strain BE2-5]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment