Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   D4I31_RS06470 Genome accession   NZ_CP032908
Coordinates   1347044..1349020 (-) Length   658 a.a.
NCBI ID   WP_139535070.1    Uniprot ID   -
Organism   Helicobacter pylori strain 23-A-EK1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1342044..1354020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4I31_RS06445 - 1342108..1342500 (+) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -
  D4I31_RS06450 - 1342510..1343733 (+) 1224 WP_050841301.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  D4I31_RS06455 - 1343746..1344690 (+) 945 WP_120913977.1 thiamine pyrophosphate-dependent enzyme -
  D4I31_RS06460 purB 1344799..1346121 (+) 1323 WP_139535068.1 adenylosuccinate lyase -
  D4I31_RS06465 - 1346186..1347019 (+) 834 WP_139535069.1 outer membrane protein -
  D4I31_RS06470 uvrB 1347044..1349020 (-) 1977 WP_139535070.1 excinuclease ABC subunit UvrB Machinery gene
  D4I31_RS06475 - 1349061..1349843 (-) 783 WP_139535071.1 hypothetical protein -
  D4I31_RS06480 - 1349840..1350274 (-) 435 WP_139534482.1 hypothetical protein -
  D4I31_RS08450 - 1350362..1350886 (-) 525 WP_236635748.1 hypothetical protein -
  D4I31_RS06485 - 1350873..1353326 (-) 2454 WP_139534437.1 DUF3519 domain-containing protein -
  D4I31_RS06490 - 1353295..1353495 (+) 201 WP_139534435.1 hypothetical protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75969.50 Da        Isoelectric Point: 6.7308

>NTDB_id=280924 D4I31_RS06470 WP_139535070.1 1347044..1349020(-) (uvrB) [Helicobacter pylori strain 23-A-EK1]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRTYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKNNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKVRYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDVDKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
LSMQKAFEITSYRRAKQEEFNKLHNITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=280924 D4I31_RS06470 WP_139535070.1 1347044..1349020(-) (uvrB) [Helicobacter pylori strain 23-A-EK1]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTACACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAACGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACTTCGCTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCACTTATAAGAGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACGGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCTAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCCAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAGAATAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAGATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGTGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGACTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGTGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCCAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CTAAGCATGCAAAAAGCCTTTGAAATTACAAGCTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATAATATCAC
TCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGCTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB/uvrC motif (UVR)

(623-657)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.17

100

0.495
  uvrB Streptococcus pneumoniae D39

49.17

100

0.495
  uvrB Streptococcus pneumoniae TIGR4

49.17

100

0.495