Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   D4I62_RS06390 Genome accession   NZ_CP032907
Coordinates   1333325..1335301 (-) Length   658 a.a.
NCBI ID   WP_139533925.1    Uniprot ID   -
Organism   Helicobacter pylori strain 24-A-EK1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1328325..1340301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4I62_RS06365 - 1328398..1328790 (+) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -
  D4I62_RS06370 - 1328800..1330023 (+) 1224 WP_108253187.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  D4I62_RS06375 - 1330036..1330980 (+) 945 WP_000238149.1 thiamine pyrophosphate-dependent enzyme -
  D4I62_RS06380 purB 1331090..1332412 (+) 1323 WP_139533709.1 adenylosuccinate lyase -
  D4I62_RS06385 - 1332481..1333314 (+) 834 WP_139533710.1 outer membrane protein -
  D4I62_RS06390 uvrB 1333325..1335301 (-) 1977 WP_139533925.1 excinuclease ABC subunit UvrB Machinery gene
  D4I62_RS06395 - 1335342..1335928 (-) 587 Protein_1217 hypothetical protein -
  D4I62_RS08290 - 1335974..1336174 (-) 201 WP_139533711.1 hypothetical protein -
  D4I62_RS06405 - 1336134..1339658 (-) 3525 WP_139533712.1 DUF3519 domain-containing protein -
  D4I62_RS08295 - 1339627..1339827 (+) 201 Protein_1220 hypothetical protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75960.36 Da        Isoelectric Point: 6.7308

>NTDB_id=280880 D4I62_RS06390 WP_139533925.1 1333325..1335301(-) (uvrB) [Helicobacter pylori strain 24-A-EK1]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISTTGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECTKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=280880 D4I62_RS06390 WP_139533925.1 1333325..1335301(-) (uvrB) [Helicobacter pylori strain 24-A-EK1]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCTTTAACAAAAAGCTT
GAAAAATAACAACCATTATCAAACTCTAGTGGGGGTTACAGGAAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGGAGGGATTTATT
TATTGAAAAAGACAGCTCTATTAACGATGATTTAGAGCGTTTAAGATTGAGCGCGACCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGTGAGAAGCGCGCTTACAAGAGCTTTTTATTAAAGCTAGTGGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACTGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAATTTGCTGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCACGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGTAAAGCCCCTAACGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTAGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATTATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAACCACT
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGTGCTAAGCAAGAAGAGTTTAATAAAATTCATAATATTAC
TCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCTTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCACGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497