Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C7J89_RS06065 Genome accession   NZ_CP027846
Coordinates   1241027..1241656 (+) Length   209 a.a.
NCBI ID   WP_061855637.1    Uniprot ID   A0A151A174
Organism   Staphylococcus kloosii strain ATCC 43959     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1236027..1246656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7J89_RS06035 (C7J89_06030) - 1236106..1236822 (+) 717 WP_103295268.1 type 1 glutamine amidotransferase -
  C7J89_RS06040 (C7J89_06035) - 1236889..1237875 (-) 987 WP_106884396.1 aromatic acid exporter family protein -
  C7J89_RS06045 (C7J89_06040) map 1238034..1238786 (+) 753 WP_061855633.1 type I methionyl aminopeptidase -
  C7J89_RS06050 (C7J89_06045) - 1238893..1239279 (+) 387 WP_061855634.1 hypothetical protein -
  C7J89_RS06055 (C7J89_06050) liaF 1239296..1239997 (+) 702 WP_103295994.1 cell wall-active antibiotics response protein LiaF -
  C7J89_RS06060 (C7J89_06055) vraS 1239994..1241037 (+) 1044 WP_103295995.1 sensor histidine kinase Regulator
  C7J89_RS06065 (C7J89_06060) vraR 1241027..1241656 (+) 630 WP_061855637.1 response regulator transcription factor Regulator
  C7J89_RS06070 (C7J89_06065) - 1241729..1242814 (-) 1086 Protein_1183 YihY/virulence factor BrkB family protein -
  C7J89_RS06075 (C7J89_06070) - 1243069..1243350 (-) 282 WP_061855639.1 hypothetical protein -
  C7J89_RS06080 (C7J89_06075) - 1243357..1243821 (-) 465 WP_103295996.1 low molecular weight protein-tyrosine-phosphatase -
  C7J89_RS06085 (C7J89_06080) - 1243953..1244156 (+) 204 WP_048793238.1 DUF1128 family protein -
  C7J89_RS06090 (C7J89_06085) - 1244169..1245407 (+) 1239 WP_103295997.1 aminopeptidase -
  C7J89_RS06095 (C7J89_06090) - 1245438..1245959 (+) 522 WP_061855642.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23664.29 Da        Isoelectric Point: 4.8783

>NTDB_id=280879 C7J89_RS06065 WP_061855637.1 1241027..1241656(+) (vraR) [Staphylococcus kloosii strain ATCC 43959]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIQLAHELKPDLILMDLLMDDMDGVDATAQVKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSAKDIAEAIRKTQNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=280879 C7J89_RS06065 WP_061855637.1 1241027..1241656(+) (vraR) [Staphylococcus kloosii strain ATCC 43959]
ATGCCAATTAAAGTTTTATTTGTTGATGACCATGAAATGGTACGTATTGGGATATCAAGTTATTTATCAACACAACCAGA
TATAGAAGTAGTAGGAGAAGGTAAGTCAGGTAAAGAAGCAATTCAATTAGCGCATGAATTAAAACCAGATTTAATCTTAA
TGGATTTATTGATGGATGATATGGATGGAGTAGACGCTACTGCGCAAGTAAAAAAAGATTTACCACATATCAAAGTTGTA
ATGTTAACAAGTTACATTGAGGATAATGAAGTTTATCGTGCATTAGATTCTGGTGTAGATAGTTATATCTTAAAAACGAC
GAGTGCTAAAGATATTGCAGAAGCAATACGTAAAACACAAAATGATGAATCTGTTTTTGAAGCAGAAGTTTTAGTGAAAA
TGCGTAATCGCATGAAGCAACGTGCAGAATTATATGAGATGTTAACTGAAAGAGAAATGGAAATTTTATTACTTATCGCT
AAAGGTTATTCTAACCAAGAAATTGCTAGTGCATCTCACATTACAATTAAGACGGTAAAAACACACGTTAGTAATATATT
AAGTAAATTAGAAGTGCAAGATAGAACGCAAGCTGTTATATACGCATTTCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A151A174

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment