Detailed information NTG0280878

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C7J89_RS06060
• Genome accession: NZ_CP027846
• Coordinates: 1239994..1241037 (+)
• Length: 347 a.a.
• NCBI ID: WP_103295995.1
• Uniprot ID: A0A921H2U2
• Organism: Staphylococcus kloosii strain ATCC 43959
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1234994..1246037

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7J89_RS06035 (C7J89_06030)	-	1236106..1236822 (+)	717	WP_103295268.1	type 1 glutamine amidotransferase	-
C7J89_RS06040 (C7J89_06035)	-	1236889..1237875 (-)	987	WP_106884396.1	aromatic acid exporter family protein	-
C7J89_RS06045 (C7J89_06040)	map	1238034..1238786 (+)	753	WP_061855633.1	type I methionyl aminopeptidase	-
C7J89_RS06050 (C7J89_06045)	-	1238893..1239279 (+)	387	WP_061855634.1	hypothetical protein	-
C7J89_RS06055 (C7J89_06050)	liaF	1239296..1239997 (+)	702	WP_103295994.1	cell wall-active antibiotics response protein LiaF	-
C7J89_RS06060 (C7J89_06055)	vraS	1239994..1241037 (+)	1044	WP_103295995.1	sensor histidine kinase	Regulator
C7J89_RS06065 (C7J89_06060)	vraR	1241027..1241656 (+)	630	WP_061855637.1	response regulator transcription factor	Regulator
C7J89_RS06070 (C7J89_06065)	-	1241729..1242814 (-)	1086	Protein_1183	YihY/virulence factor BrkB family protein	-
C7J89_RS06075 (C7J89_06070)	-	1243069..1243350 (-)	282	WP_061855639.1	hypothetical protein	-
C7J89_RS06080 (C7J89_06075)	-	1243357..1243821 (-)	465	WP_103295996.1	low molecular weight protein-tyrosine-phosphatase	-
C7J89_RS06085 (C7J89_06080)	-	1243953..1244156 (+)	204	WP_048793238.1	DUF1128 family protein	-
C7J89_RS06090 (C7J89_06085)	-	1244169..1245407 (+)	1239	WP_103295997.1	aminopeptidase	-
C7J89_RS06095 (C7J89_06090)	-	1245438..1245959 (+)	522	WP_061855642.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39935.20 Da
• Isoelectric Point: 5.6132

>NTDB_id=280878 C7J89_RS06060 WP_103295995.1 1239994..1241037(+) (vraS) [Staphylococcus kloosii strain ATCC 43959]
MNHYIRAIGSMLILVYSTLIAFFFIDKVFVNIMYFQGMFYTQIFGIPVFLFLNLLIIFLCIIVGSVLAYKINQQNHWLQR
QIERSIEGQTVGVNDQDIELYNETIELYHTLVPLNQEVHKLRMKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVTDLQKKVPMKVVHDI
EDFSVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNQADYLLLRVQDNGIGFNVDENTEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLDKEELDAN

Nucleotide

• Length: 1044 bp

>NTDB_id=280878 C7J89_RS06060 WP_103295995.1 1239994..1241037(+) (vraS) [Staphylococcus kloosii strain ATCC 43959]
ATGAATCACTACATAAGAGCTATAGGTTCAATGTTGATCTTAGTATACAGTACGCTAATTGCATTTTTTTTTATAGACAA
AGTTTTTGTTAATATAATGTACTTTCAAGGTATGTTTTATACGCAAATTTTTGGTATACCAGTGTTTCTATTTTTAAATT
TATTAATTATATTTTTGTGTATCATAGTTGGTTCGGTATTAGCATATAAGATTAATCAACAGAACCATTGGCTACAACGC
CAAATAGAACGCTCTATCGAAGGACAAACGGTTGGTGTGAATGATCAAGACATCGAACTGTACAATGAAACTATTGAGTT
ATACCATACACTTGTACCGTTAAATCAAGAAGTACATAAACTGAGAATGAAAACGCAAAATTTAACGAATGAGTCATATA
ATATGAATGACGTAAAAGTTAAAAAAATCATTGAAGATGAACGTCAAAGACTTGCAAGAGAACTACATGATTCAGTGAGC
CAGCAATTATTTGCTGCTAGTATGATGTTATCCGCAATTAAGGAAACCGAACTCGCACCACCATTAGATCAACAAATACC
AACTTTAGAAAAAATGGTGCAAGATTCTCAATTAGAAATGAGAGCTTTACTCTTACATTTAAGACCTATTGGCCTAAAAG
ATAAGTCATTAGGTGAAGGTATTAAAGACTTAGTAACTGATTTACAGAAAAAAGTACCGATGAAAGTCGTACATGATATT
GAGGACTTTTCAGTACCAAAAGGTATAGAAGACCATCTATTTAGAATCACACAAGAAGCGATTTCTAATACATTACGTCA
TTCAAAAGGAACGAAAGTTACAATAGAGTTGTTTAATCAAGCTGATTACTTGTTACTACGTGTGCAAGATAATGGTATAG
GTTTTAATGTAGATGAAAATACTGAACAAAGTTATGGTTTAAAAAATATGCGTGAACGTGCATTAGAAATAGGTGCAACA
TTCCATATTGTTTCTCTACCCGATTCAGGTACAAGAATAGAAGTGAAAGCGCCATTAGATAAGGAGGAATTGGATGCCAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.047	98.847	0.87