Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   VC0395_RS12745 Genome accession   NC_009457
Coordinates   1576762..1579005 (-) Length   747 a.a.
NCBI ID   WP_000173776.1    Uniprot ID   -
Organism   Vibrio cholerae O395     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1571762..1584005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VC0395_RS12725 (VC0395_A1466) kdsB 1573055..1573813 (-) 759 WP_000011329.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  VC0395_RS12730 (VC0395_A1467) - 1573813..1573992 (-) 180 WP_000350068.1 Trm112 family protein -
  VC0395_RS12735 (VC0395_A1468) lpxK 1573973..1574980 (-) 1008 WP_002034410.1 tetraacyldisaccharide 4'-kinase -
  VC0395_RS12740 (VC0395_A1469) msbA 1574983..1576731 (-) 1749 WP_000052153.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  VC0395_RS12745 (VC0395_A1470) comEC 1576762..1579005 (-) 2244 WP_000173776.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  VC0395_RS12750 (VC0395_A1471) - 1579014..1579544 (+) 531 WP_001881633.1 DUF2062 domain-containing protein -
  VC0395_RS12755 (VC0395_A1472) lolE 1579659..1580903 (-) 1245 WP_000493010.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  VC0395_RS12760 (VC0395_A1473) lolD 1580904..1581590 (-) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  VC0395_RS12765 (VC0395_A1474) lolC 1581583..1582791 (-) 1209 WP_000468900.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  VC0395_RS12770 (VC0395_A1475) - 1582967..1583542 (+) 576 WP_000999601.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 84511.71 Da        Isoelectric Point: 7.7612

>NTDB_id=28082 VC0395_RS12745 WP_000173776.1 1576762..1579005(-) (comEC) [Vibrio cholerae O395]
MTLLSNYWSLISFSITVLSAPYWPWMPSWGWAWLCLIVMVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGP
DIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTRPRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYM
AQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHTSPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHI
GIAFSVGYFLGLGMMRFHAQLLWSPFVCGALLAVLYAWLAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVL
LWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKALLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVI
VPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQFADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMIG
LWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDTGSSWPGGSYVQSVIEPMLQQRGLRQVDGVILSHLDNDHAGDW
QGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFTVLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEW
LLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLAIASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFY
LDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=28082 VC0395_RS12745 WP_000173776.1 1576762..1579005(-) (comEC) [Vibrio cholerae O395]
ATGACTCTCTTGTCGAATTACTGGTCTCTCATTTCTTTTTCGATCACCGTGCTGTCTGCCCCTTATTGGCCTTGGATGCC
GAGTTGGGGTTGGGCTTGGTTATGCCTTATTGTTATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCT
TCGTGGCTGCCATACTAACCATTGTGCTACAGGGCAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCG
GATATTATCATAAAAGGCCGTGTTGACAGCTTTTTTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGA
AGTGAATGGACAAACCTTAAACAAAATGACTCGCCCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGATC
GCGTCGAATTTTCGGTAACTCTCAAGCCGATAGTGGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATG
GCGCAATCTGTCGTCGCACGAGCGGTCGTAAAACCTGACACTGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAG
TTTGTTTTTTGAGCTAGAGCAATTAACGCATACCAGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAA
AAGGTATTGATGAGCAAGAGTGGCAAGCCTTACGCAATAGTGGCTTAATTCATTTAGTGGCCATTTCGGGGCTGCACATT
GGTATCGCTTTTAGCGTGGGGTATTTTCTCGGGCTCGGCATGATGCGTTTTCATGCTCAGTTATTGTGGTCCCCTTTTGT
GTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGGCTGGCCGGATTTACGTTGCCTACTCAGCGTGCATTGATTATGTGCT
TACTCAATGTGGCGTTGATCATGTTGGCTTTTCCTCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGGTCTTG
CTTTGGTCGCCATTCGCCTCACTTTCAAACAGTTTCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGC
CAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCTCTTCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCA
CGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGCAGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATT
GTCCCAGCTTTGTTTTTGGGTCTATTACTCATGGTGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTG
GACGTTTTTACCGCTCGATTGGGCTTTGCAGTTTGCCGATGTAGGCTGGTGGGTGGTCCCCAGCAAAGTACAAGGTGTGG
TCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCGATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATTGGC
TTATGGTGGTGGTTTCCCTCTCTCACTCCACTTTGGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGAT
TGAGCAAGATGAGCGAGCAATTGTCTACGATACAGGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGATTGAGC
CTATGCTCCAACAGCGGGGGCTACGCCAAGTGGATGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGG
CAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGATTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGG
TGAAAGCTGGCAGTGGCAATCTCTCCATTTTACGGTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATT
CGTGTGTGATTCGTATGACCGATACTCAGTCTAACCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGG
CTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTGAGGTGATGATCGTGCCGCACCACGGCAGTAAAACATCGTCCACCGC
AGAGTTTATTGCCCAAGTGAATCCCAAACTTGCGATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGC
AAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGAGTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTTTCTAT
CTAGATCAGCTGGATTGGTTTACCCAGCGTAGCCTTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGA
ATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-464)

Domain of unknown function (DUF4131) (DUF4131)

(21-173)

Metallo-beta-lactamase superfamily (Lactamase_B)

(499-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

100

100

1
  comEC Vibrio parahaemolyticus RIMD 2210633

41.215

100

0.418
  comEC Vibrio campbellii strain DS40M4

40.957

100

0.412

Multiple sequence alignment