Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   D4J22_RS02180 Genome accession   NZ_CP032905
Coordinates   423831..425807 (+) Length   658 a.a.
NCBI ID   WP_139547641.1    Uniprot ID   -
Organism   Helicobacter pylori strain 26-A-EK1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 418831..430807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4J22_RS02150 - 419539..420309 (+) 771 WP_021176506.1 HP1117 family Sel1-like repeat protein -
  D4J22_RS08270 - 420547..420747 (-) 201 WP_139546954.1 hypothetical protein -
  D4J22_RS08275 - 420716..423092 (+) 2377 Protein_415 DUF3519 domain-containing protein -
  D4J22_RS02175 - 423099..423761 (+) 663 WP_139546957.1 hypothetical protein -
  D4J22_RS02180 uvrB 423831..425807 (+) 1977 WP_139547641.1 excinuclease ABC subunit UvrB Machinery gene
  D4J22_RS02185 - 425831..426664 (-) 834 WP_139546958.1 outer membrane protein -
  D4J22_RS02190 purB 426730..428052 (-) 1323 WP_139546959.1 adenylosuccinate lyase -
  D4J22_RS02195 - 428161..429105 (-) 945 WP_000238160.1 thiamine pyrophosphate-dependent enzyme -
  D4J22_RS02200 - 429118..430341 (-) 1224 WP_000124331.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  D4J22_RS02205 - 430351..430743 (-) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75932.37 Da        Isoelectric Point: 6.8803

>NTDB_id=280769 D4J22_RS02180 WP_139547641.1 423831..425807(+) (uvrB) [Helicobacter pylori strain 26-A-EK1]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRTYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFDREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKNNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARGERVLITTLTKKMAEELCKYYAEWGLKVRYMHS
EIDAIERNHLIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKLHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=280769 D4J22_RS02180 WP_139547641.1 423831..425807(+) (uvrB) [Helicobacter pylori strain 26-A-EK1]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGTCATAATAAGACCTTATGCGCGCAGCTATATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGTGCAACCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGCAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCACTTATAAGAGCTTTTTACTCAAACTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGCGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGACGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTCACCGGTAAAGCCCCTAACGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGATCGGGAATTTTTAGTCATTGTAGATGAAAGCCATGTGAGTTTGCC
GCAATTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAGAATAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCCAGAGGTGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGTGCGTTACATGCATAGC
GAAATTGATGCGATTGAAAGGAATCACCTTATCCGCTCTTTAAGGCTTAAGGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAACCACT
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGCGCCAAGCAAGAAGAGTTCAATAAGCTTCATAATATCAC
TCCCAAAACCGTTACTCGTGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATGCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498

Multiple sequence alignment