Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   D4K40_RS02205 Genome accession   NZ_CP032902
Coordinates   427788..429764 (+) Length   658 a.a.
NCBI ID   WP_139521222.1    Uniprot ID   -
Organism   Helicobacter pylori strain 280-A-EK1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 422788..434764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4K40_RS02190 - 423550..424320 (+) 771 WP_139520488.1 HP1117 family Sel1-like repeat protein -
  D4K40_RS08195 - 424566..424766 (-) 201 WP_000135787.1 hypothetical protein -
  D4K40_RS02195 - 424735..426995 (+) 2261 Protein_417 DUF3519 domain-containing protein -
  D4K40_RS02200 - 427002..427737 (+) 736 Protein_418 hypothetical protein -
  D4K40_RS02205 uvrB 427788..429764 (+) 1977 WP_139521222.1 excinuclease ABC subunit UvrB Machinery gene
  D4K40_RS02210 - 429761..430594 (-) 834 WP_139520490.1 outer membrane protein -
  D4K40_RS02215 purB 430660..431982 (-) 1323 WP_139520491.1 adenylosuccinate lyase -
  D4K40_RS02220 - 432091..433035 (-) 945 WP_000238160.1 thiamine pyrophosphate-dependent enzyme -
  D4K40_RS02225 - 433048..434271 (-) 1224 WP_078271203.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  D4K40_RS02230 - 434281..434673 (-) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75965.39 Da        Isoelectric Point: 6.7808

>NTDB_id=280643 D4K40_RS02205 WP_139521222.1 427788..429764(+) (uvrB) [Helicobacter pylori strain 280-A-EK1]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKIHHITPKTVTRALEEELKLRDDEIRIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=280643 D4K40_RS02205 WP_139521222.1 427788..429764(+) (uvrB) [Helicobacter pylori strain 280-A-EK1]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGGAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTACGGTTTGGGTAACCCTGAAGAATATTTGAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAGCTCGC
TTTAAGGTTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCGACCGGTGTGTGTAAGGGCATTGAAAATTATGCGCGCCATTTTACAGGCAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATTTTTGAGAGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAATTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCCAGAGATGAAAGGGTGCTAATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
CTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGAGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAACCACT
CAAAGCATGCAAAAAGCCTTTGAGATTACGAGTTACAGGCGCGCCAAGCAAGAAGAGTTTAATAAAATTCATCATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGCTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCTTTAAAAA
AGGACAAAATCCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

UvrB/uvrC motif (UVR)

(623-657)

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498