Detailed information NTG0280462

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C7K40_RS07245
• Genome accession: NZ_CP027771
• Coordinates: 1438394..1439395 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain DMG1800716
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1433394..1444395

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7K40_RS07230 (C7K40_07225)	thrS	1433564..1435507 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
C7K40_RS07235 (C7K40_07230)	-	1435929..1437263 (-)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
C7K40_RS07240 (C7K40_07235)	-	1437265..1438263 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
C7K40_RS07245 (C7K40_07240)	ccpA	1438394..1439395 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
C7K40_RS07250 (C7K40_07245)	-	1439569..1440654 (+)	1086	WP_002990707.1	Xaa-Pro peptidase family protein	-
C7K40_RS07255 (C7K40_07250)	-	1440703..1441368 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
C7K40_RS07260 (C7K40_07255)	-	1441379..1441756 (+)	378	WP_002985686.1	VOC family protein	-
C7K40_RS07265 (C7K40_07260)	-	1441901..1442827 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
C7K40_RS07270 (C7K40_07265)	-	1443038..1443721 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=280462 C7K40_RS07245 WP_002985680.1 1438394..1439395(-) (ccpA) [Streptococcus pyogenes strain DMG1800716]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=280462 C7K40_RS07245 WP_002985680.1 1438394..1439395(-) (ccpA) [Streptococcus pyogenes strain DMG1800716]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559