Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C7J90_RS11375 Genome accession   NZ_CP027770
Coordinates   2381369..2381998 (-) Length   209 a.a.
NCBI ID   WP_103207605.1    Uniprot ID   A0A2K3ZIJ2
Organism   Staphylococcus felis strain ATCC 49168     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2376369..2386998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7J90_RS11345 (C7J90_11345) - 2376737..2377978 (-) 1242 WP_103207614.1 aminopeptidase -
  C7J90_RS11350 (C7J90_11350) - 2377996..2378205 (-) 210 WP_262633092.1 DUF1128 domain-containing protein -
  C7J90_RS11355 (C7J90_11355) - 2378340..2378804 (+) 465 WP_103207612.1 low molecular weight protein-tyrosine-phosphatase -
  C7J90_RS11360 (C7J90_11360) - 2378806..2379093 (+) 288 WP_103207611.1 YtxH domain-containing protein -
  C7J90_RS11365 (C7J90_11365) - 2379456..2380679 (+) 1224 WP_103207609.1 YihY/virulence factor BrkB family protein -
  C7J90_RS11370 (C7J90_11370) - 2380710..2381282 (+) 573 WP_103207607.1 carbonic anhydrase -
  C7J90_RS11375 (C7J90_11375) vraR 2381369..2381998 (-) 630 WP_103207605.1 response regulator transcription factor Regulator
  C7J90_RS11380 (C7J90_11380) vraS 2381988..2383031 (-) 1044 WP_103207603.1 sensor histidine kinase Regulator
  C7J90_RS11385 (C7J90_11385) liaF 2383028..2383729 (-) 702 WP_103207601.1 cell wall-active antibiotics response protein LiaF -
  C7J90_RS11390 (C7J90_11390) - 2383742..2384131 (-) 390 WP_103207599.1 hypothetical protein -
  C7J90_RS11395 (C7J90_11395) map 2384226..2384987 (-) 762 WP_103207598.1 type I methionyl aminopeptidase -
  C7J90_RS11400 (C7J90_11400) - 2385078..2386082 (+) 1005 WP_174688362.1 aromatic acid exporter family protein -
  C7J90_RS11405 (C7J90_11405) - 2386162..2386887 (-) 726 WP_103207595.1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23518.22 Da        Isoelectric Point: 4.8838

>NTDB_id=280419 C7J90_RS11375 WP_103207605.1 2381369..2381998(-) (vraR) [Staphylococcus felis strain ATCC 49168]
MTIRVLFVDDHEMVRIGISSYLSTQPDIEVVGEGESGKDAIEKAKLLKPDLILMDLVMTDMDGVEATTYIKKEMPQIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIASAIRKTSQGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=280419 C7J90_RS11375 WP_103207605.1 2381369..2381998(-) (vraR) [Staphylococcus felis strain ATCC 49168]
ATGACAATTAGAGTATTATTTGTAGATGATCATGAAATGGTTCGTATTGGGATATCAAGTTACTTATCAACTCAACCTGA
TATAGAAGTAGTTGGTGAAGGGGAGTCGGGCAAAGATGCTATCGAAAAAGCAAAACTGTTAAAGCCTGATTTGATCTTAA
TGGATTTAGTGATGACTGACATGGATGGTGTCGAGGCAACGACTTATATTAAAAAGGAAATGCCGCAGATTAAAGTAGTC
ATGCTAACAAGCTATATAGAGGATAAAGAGGTGTATCGCGCGCTTGATGCGGGTGTTGATAGTTATATCCTAAAAACGAC
AAGTGCAAGTGATATTGCGTCAGCTATTCGTAAAACGAGTCAAGGTGAATCTGTTTTTGAAGCGGAAGTCCTTGTTAAAA
TGAGAAATCGTATGAAACAAAGAGCTGAATTGTATGAATTGTTAACTGAAAGAGAAATGGAAATATTATTATTAATTGCC
AAGGGATATTCTAATCAGGAGATAGCAAGTGCATCACATATTACCATAAAGACCGTTAAAACACATGTTAGTAATATATT
GAGTAAGTTGGAAGTACAAGACCGTACTCAAGCAGTCATTTACGCATTTCAGCACGGATTAATCGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K3ZIJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.995

100

0.89
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment