Detailed information NTG0280420

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C7J90_RS11380
• Genome accession: NZ_CP027770
• Coordinates: 2381988..2383031 (-)
• Length: 347 a.a.
• NCBI ID: WP_103207603.1
• Uniprot ID: A0A2K3ZIM8
• Organism: Staphylococcus felis strain ATCC 49168
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2376988..2388031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7J90_RS11350 (C7J90_11350)	-	2377996..2378205 (-)	210	WP_262633092.1	DUF1128 domain-containing protein	-
C7J90_RS11355 (C7J90_11355)	-	2378340..2378804 (+)	465	WP_103207612.1	low molecular weight protein-tyrosine-phosphatase	-
C7J90_RS11360 (C7J90_11360)	-	2378806..2379093 (+)	288	WP_103207611.1	YtxH domain-containing protein	-
C7J90_RS11365 (C7J90_11365)	-	2379456..2380679 (+)	1224	WP_103207609.1	YihY/virulence factor BrkB family protein	-
C7J90_RS11370 (C7J90_11370)	-	2380710..2381282 (+)	573	WP_103207607.1	carbonic anhydrase	-
C7J90_RS11375 (C7J90_11375)	vraR	2381369..2381998 (-)	630	WP_103207605.1	response regulator transcription factor	Regulator
C7J90_RS11380 (C7J90_11380)	vraS	2381988..2383031 (-)	1044	WP_103207603.1	sensor histidine kinase	Regulator
C7J90_RS11385 (C7J90_11385)	liaF	2383028..2383729 (-)	702	WP_103207601.1	cell wall-active antibiotics response protein LiaF	-
C7J90_RS11390 (C7J90_11390)	-	2383742..2384131 (-)	390	WP_103207599.1	hypothetical protein	-
C7J90_RS11395 (C7J90_11395)	map	2384226..2384987 (-)	762	WP_103207598.1	type I methionyl aminopeptidase	-
C7J90_RS11400 (C7J90_11400)	-	2385078..2386082 (+)	1005	WP_174688362.1	aromatic acid exporter family protein	-
C7J90_RS11405 (C7J90_11405)	-	2386162..2386887 (-)	726	WP_103207595.1	glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40184.49 Da
• Isoelectric Point: 5.1680

>NTDB_id=280420 C7J90_RS11380 WP_103207603.1 2381988..2383031(-) (vraS) [Staphylococcus felis strain ATCC 49168]
MNHYVRTIGSMLILVYSMFTAFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLIVIFLCIIVGSVIAYKINQQNDWLQQ
QIERAFEGETVGVNDQQLELYNETLEIYRSLVPLNQELHKMRIKTQNLTNESYNLNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETNLNPPLDQQIPTLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIRSLVTELQKKVPMKVIQEI
DEFDVPKGIEDHLFRITQEAISNTLRHAKGEQVTVELLKREDYLLLRIQDDGIGFNVDDKIEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEESHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=280420 C7J90_RS11380 WP_103207603.1 2381988..2383031(-) (vraS) [Staphylococcus felis strain ATCC 49168]
ATGAATCACTATGTCAGAACGATTGGATCAATGCTCATACTAGTTTACAGTATGTTTACAGCTTTCTTTTTTATCGATAA
AGTTTTTGTGAATATCATATTTTTTCAAGGTATGTTTTACACTCAAATCTTCGGTATTCCTGTATTTTTATTTCTTAACT
TAATTGTCATTTTTTTGTGTATTATTGTGGGTAGTGTAATAGCGTATAAGATTAATCAACAAAATGATTGGTTACAACAA
CAGATTGAGCGTGCATTTGAAGGTGAAACAGTCGGTGTTAACGATCAGCAACTAGAGCTGTATAATGAAACATTAGAGAT
TTACCGTTCATTGGTACCGCTCAATCAAGAATTACATAAAATGCGAATTAAAACTCAAAATTTGACAAATGAATCTTATA
ACTTAAATGATATAAAAGTAAAAAAAATAATTGAAGATGAACGTCAACGGTTAGCTAGAGAGCTTCACGATAGCGTTTCG
CAGCAATTGTTTGCAGCTAGTATGATGTTATCAGCTATTAAAGAAACAAACTTAAATCCACCACTTGATCAACAGATACC
AACACTTGAAAAAATGATTCAAGACTCACAACTTGAAATGAGAGCATTATTATTACACCTACGTCCAATAGGTTTGAAGG
ATAAATCATTAGGTGAAGGCATACGATCGTTAGTGACTGAATTACAAAAGAAAGTACCTATGAAAGTTATACAAGAAATT
GATGAGTTTGATGTTCCAAAGGGTATAGAAGATCACTTATTTAGAATCACACAAGAGGCAATCTCCAATACGTTACGTCA
TGCTAAGGGTGAACAAGTGACGGTTGAATTGTTAAAAAGAGAAGACTATTTATTATTGCGTATTCAAGATGATGGTATCG
GCTTTAATGTGGACGATAAAATTGAACAAAGTTATGGTTTGAAAAATATGCGTGAAAGAGCAATTGAAATTGGTGCAACT
TTTCATATCGTCTCTTTGCCTGATGCAGGAACACGTATCGAGGTTAAAGCACCATTAGAAAAGGAGGAAAGTCATGACAA
TTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2K3ZIM8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.997	100	0.83