Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   SPYM_RS01340 Genome accession   NC_009332
Coordinates   254988..256058 (+) Length   356 a.a.
NCBI ID   WP_010921893.1    Uniprot ID   A0A4U9C068
Organism   Streptococcus pyogenes str. Manfredo     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 249988..261058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS01325 (SpyM50227) amiA 250516..252486 (+) 1971 WP_011017333.1 peptide ABC transporter substrate-binding protein Regulator
  SPYM_RS01330 (SpyM50228) amiC 252551..254053 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  SPYM_RS01335 (SpyM50229) amiD 254053..254979 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  SPYM_RS01340 (SpyM50230) amiE 254988..256058 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  SPYM_RS01345 (SpyM50231) amiF 256051..256974 (+) 924 WP_002986000.1 ATP-binding cassette domain-containing protein Regulator
  SPYM_RS10140 - 257012..257095 (-) 84 Protein_224 IS3 family transposase -
  SPYM_RS09915 - 257122..257301 (-) 180 WP_111695866.1 transposase -
  SPYM_RS09960 - 257599..258611 (-) 1013 Protein_226 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39703.77 Da        Isoelectric Point: 5.6707

>NTDB_id=27846 SPYM_RS01340 WP_010921893.1 254988..256058(+) (amiE) [Streptococcus pyogenes str. Manfredo]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=27846 SPYM_RS01340 WP_010921893.1 254988..256058(+) (amiE) [Streptococcus pyogenes str. Manfredo]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATTGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C068

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment