Detailed information NTG0277951

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPV_RS09565
• Genome accession: NZ_CP027540
• Coordinates: 1791316..1792326 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990602.1
• Uniprot ID: A0A0H2ZQ65
• Organism: Streptococcus pneumoniae strain D39V
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1786316..1797326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPV_RS09535 (SPV_1791)	-	1786336..1787550 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPV_RS09540 (SPV_1792)	-	1787706..1787999 (-)	294	WP_000977365.1	hypothetical protein	-
SPV_RS09545 (SPV_1793)	-	1788161..1788613 (+)	453	WP_106269362.1	universal stress protein	-
SPV_RS09550 (SPV_1794)	-	1788648..1790036 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
SPV_RS09555 (SPV_1796)	-	1790102..1791064 (+)	963	WP_001124777.1	asparaginase	-
SPV_RS09560 (SPV_1795)	-	1791061..1791252 (-)	192	WP_001092029.1	hypothetical protein	-
SPV_RS09565 (SPV_1797)	ccpA	1791316..1792326 (-)	1011	WP_000990602.1	catabolite control protein A	Regulator
SPV_RS09570 (SPV_1798)	-	1792751..1793350 (-)	600	WP_000866719.1	response regulator transcription factor	-
SPV_RS09575 (SPV_1799)	-	1793352..1794449 (-)	1098	WP_000893546.1	sensor histidine kinase	-
SPV_RS09580 (SPV_1800)	-	1794449..1795186 (-)	738	WP_000832834.1	ABC transporter permease	-
SPV_RS09585 (SPV_1801)	-	1795188..1796072 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
SPV_RS09590 (SPV_1802)	-	1796059..1796253 (-)	195	WP_000820180.1	hypothetical protein	-
SPV_RS09595 (SPV_1803)	-	1796250..1796456 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37042.99 Da
• Isoelectric Point: 5.3212

>NTDB_id=277951 SPV_RS09565 WP_000990602.1 1791316..1792326(-) (ccpA) [Streptococcus pneumoniae strain D39V]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTATVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=277951 SPV_RS09565 WP_000990602.1 1791316..1792326(-) (ccpA) [Streptococcus pneumoniae strain D39V]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAGCCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0H2ZQ65

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	100	100	1
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.402	98.512	0.565