Detailed information NTG0277746

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: AM462_RS19900
• Genome accession: NZ_CP027528
• Coordinates: 4066721..4069153 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472717.1
• Uniprot ID: A0A0J1ADA4
• Organism: Acinetobacter baumannii strain AR_0083
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	4065949..4073831	4066721..4069153	within	0

Gene organization within MGE regions

Location: 4065949..4073831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AM462_RS19895 (AM462_19895)	lolD	4065949..4066635 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
AM462_RS19900 (AM462_19900)	comA/comEC	4066721..4069153 (+)	2433	WP_000472717.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AM462_RS19905 (AM462_19905)	-	4069106..4070089 (-)	984	WP_001985534.1	lysophospholipid acyltransferase family protein	-
AM462_RS19910 (AM462_19910)	sppA	4070226..4071242 (+)	1017	WP_001286615.1	signal peptide peptidase SppA	-
AM462_RS19915 (AM462_19915)	-	4071261..4072070 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
AM462_RS19920 (AM462_19920)	purN	4072135..4072764 (-)	630	WP_000975532.1	phosphoribosylglycinamide formyltransferase	-
AM462_RS19925 (AM462_19925)	purM	4072761..4073831 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92596.96 Da
• Isoelectric Point: 8.7258

>NTDB_id=277746 AM462_RS19900 WP_000472717.1 4066721..4069153(+) (comA/comEC) [Acinetobacter baumannii strain AR_0083]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQYLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSSSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSALIFIGFLLLKQPIKPFTLLVYSASLLLLMDPFSVLSAGFWLSYGACFILIRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGSVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSYLGLLEKLSLTLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHPQQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPIIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVDGYRNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHERR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=277746 AM462_RS19900 WP_000472717.1 4066721..4069153(+) (comA/comEC) [Acinetobacter baumannii strain AR_0083]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTCTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGTATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAATGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAGTAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTTTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGTCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATTAGTCGTTATT
ATCCTCAAATTTATTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCCCTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTTGTATATAGCGCAAGTCTACTGTTGCTAATGGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGTTTTATTTTAATAAGAATCTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGAGTAAGGTATTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCTTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTAGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGTATATTGCTGAGTTATTTGGGCTTATTAGAAAAACTCTCTTTAACATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATTATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGAATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAG
GCCATTTTTTTACAACATCCCCAACAAAACTGGTTAATTGACACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCTCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTATTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGATG
GTTACCGAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCCGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGTTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTGCATA
TTCCGCTAAAAAGCACTGTGGAACAAGGAACCTTAAGTTTTGTGTTGGAAAACCACAAAATAGTTTTACATGAGCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Competence protein (Competence) (243-522)

3D structure

• AlphaFold DB: A0A0J1ADA4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.272	100	0.983
comA/comEC	Acinetobacter baumannii strain A118	97.778	100	0.978
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504