Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D7U33_RS18605 Genome accession   NZ_CP032679
Coordinates   3844631..3845221 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3839631..3850221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7U33_RS18590 (D7U33_18995) uhpT 3840271..3841662 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  D7U33_RS18595 (D7U33_19000) uhpC 3841800..3843119 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  D7U33_RS18600 (D7U33_19005) uhpB 3843129..3844631 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  D7U33_RS18605 (D7U33_19010) letA 3844631..3845221 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  D7U33_RS18610 (D7U33_19015) ilvN 3845297..3845587 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  D7U33_RS18615 (D7U33_19020) ilvB 3845591..3847279 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  D7U33_RS18620 (D7U33_19025) ivbL 3847385..3847483 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  D7U33_RS18625 (D7U33_19040) tisB 3848048..3848137 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  D7U33_RS22415 ysdE 3848261..3848335 (-) 75 WP_211180519.1 protein YsdE -
  D7U33_RS18630 (D7U33_19045) emrD 3848417..3849601 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  D7U33_RS18635 (D7U33_19050) yidF 3849609..3850106 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=277565 D7U33_RS18605 WP_000633668.1 3844631..3845221(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=277565 D7U33_RS18605 WP_000633668.1 3844631..3845221(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378